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Analysis of relationship between natural death of Oncomelania hupensis snails and water level in Eastern Dongting Lake district GAO Jian-Chuan, ZHOU Yi-Biao, LI Lin-Han, WU Jin-Yi, ZHENG Sheng-Bang, SONG Xiu-Xia, HE Zhong, CAI Bin, YOU Jia-Bian, JIANG Qing-Wu Chinese Journal of Schistosomiasis Control    2015, 27 (3): 302-.   DOI: 10.16250/j.32.1374.2015023 Abstract （508）      PDF（pc） （2598KB）（116419）       Knowledge map    Save Objective Objective To study the reasons of natural death of Oncomelania hupensis snails by comparing the differences of the indicator days covered with water（DCW）in snail marshland and non?snail marshland around the build of Three Gorges Dam in Eastern Dongting Lake areas. Methods Methods Two marshlands were selected，one was a non?snail marshland（Qianliang Lake） and another was a snail marshland（Junshan Park） . The measuring points were set through the mechanical sampling. The snails and elevation of the points were surveyed，and the data of the water levels from the hydrological station were collected，and then DCWs were calculated. Results Results From 1995 to 2013，DCWs of the marshland of natural death of snails were all more than that of the snail marshland（P < 0.01） . In Qianliang Lake marshland，the difference between DCW before natural death and DCW from natural death until the dam was not significant （P = 0.23），while DCWs of the two stages both were more than that after the dam（P1 = 0.045，P2 = 0.002） . Before the build of the dam，DCW of the Qianliang Lake marshland of natural death of snails was more than that after the build of the dam（P = 0.013），and there was the same situation in Junshan Park marshland（P = 0.005） . The relationship between snail density and DCW was not significant in Junshan Park marshland（rs = 0.008， P = 0.914），and the reference range of DCW of all the measuring points was 76-251 days. Conclusion Conclusion In the eastern Dongting Lake district，the build of Three Gorges Dam and DCW may be not the direct factors affecting the natural death of snails and the latter may change the distribution of snails. Related Articles | Metrics | Comments（0）

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Evaluation on effect of treatment and assistance to advanced patients in Hunan Province from 2004 2004 to to 2013 LI Sheng-Ming, ZHAO Zheng-Yuan, PENG Zai-Zhi, WANG Zhang-Hua, LI Yuan, GUO Feng-Ying, REN Guang-Hui Chinese Journal of Schistosomiasis Control    2014, 26 (4): 362-.   Abstract （669）      PDF（pc） （1642KB）（114075）       Knowledge map    Save Objective Objective To comprehensively evaluate the effect of the program of treatment and assistance to advanced schis? tosomiasis patients in Hunan Province from 2004 to 2013. Methods Methods The fund investment of the program，the profits of hospi? tals and the improvement of the patients’health were investigated by data collection and questionnaire survey. The evaluation index system of treatment and assistance to advanced schistosomiasis in Hunan Province was constructed by the Delphi method and analytic hierarchy process，and the program was assessed comprehensively. Results Results The evaluation index system includ? ing 6 primary indices and 33 secondary indices was established. Among all the primary indices，the score of the treatment and assistance（22.25）was the highest，and that of the satisfaction assessment（8.15）was the lowest，and the score of the compre? hensive assessment was 87.06. The average cure rate of the patients was 13.08% from 2004 to 2013. More than 60% of the pa? tients’disease condition got better，and nearly 70% of the patients’psychological condition improved，and more than 70% of patients’self?help ability and social contact improved，as well as family happiness increased. In addition，the annual average cost for caretakers decreased by 2000 Yuan，and the profits of all the fixed?point hospitals for treatment and assistance in? creased. Conclusion Conclusion The effectiveness and efficiency of the treatment and assistance to advanced schistosomiasis patients in Hunan Province is obvious，and the government should continuously invest in the program. Related Articles | Metrics | Comments（0）

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Retrospective investigation of schistosomiasis endemic situation in Hunan Province HAN Yang-Qing, HU Ben-Jiao, ZHOU Ying-Cai, WANG Xin-Yao, HUANG Zhi-Wei, LIU Ke-Jian, WANG Yue-Ming, MENG Shi-Hua, LI Guang-Ping, REN Guang-Hui Chinese Journal of Schistosomiasis Control    2014, 26 (5): 491-.   Abstract （692）      PDF（pc） （2799KB）（113874）       Knowledge map    Save Objective Objective To understand the dynamic rules of schistosomiasis endemic situation before and after reaching the criteria of schistosomiasis transmission controlled or transmission interrupted，so as to provide the evidence for improving schis? tosomiasis control. Methods Methods Wuling District，Xihu District and Linli County were selected and investigated retrospectively to collect the schistosomiasis epidemiological information 10 years before they reached the criteria of transmission controlled and the subsequent years until 2008. A database of retrospective investigation was established for analyzing the trends and rules of changes of the Oncomelania hupensis snail status and infection status of cattle and human. Results Results In Wuling District，the en? demic situation was declining，and no schistosome infection persons，animals and snails were found after 1974. There was no re? bound until 2008. In Xihu District，the endemic situation reached the criteria of transmission controlled in 1997，and the endem? ic situation was stable. The human infection rate was positively correlated with the area of infection snails（r=0.584，P<0.05） . In Linli County，there were no snails，no infected persons and cattle twice，but 2 endemic rebounds，and there were positive corre? lations between the densities of living snails and the infection rates of human and animal during the endemic rebound period. Conclusion Conclusion The snail status is an important indicator of schistosomiasis endemic rebound. Therefore，the snail control is one of the most important schistosomiasis control measures. Related Articles | Metrics | Comments（0）

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The evidences for formulation of schistosomiasis control and elimination criteria: results from a large scale of retrospective investigations ZHOU Xiao-Nong, WANG Tian-Ping, LIN Dan-Dan, WEN Li-Yong, ZHONG Bo, XU Jing, LI Shi-Zhu Chinese Journal of Schistosomiasis Control    2014, 26 (5): 479-.   Abstract （652）      PDF（pc） （1634KB）（112983）       Knowledge map    Save In this study，we summarized the results from the retrospective investigation on endemic situation of schistosomia? sis that was implemented in nine provinces（autonomous region），China in 2009，demonstrated the role of these retrospective in? vestigations in accelerating the progress of schistosomiasis control in China，and clarified the great significance of the investiga? tion for summarizing the experiences for the control of schistosomiasis，and analyzing the changing patterns and affecting factors of endemic status of schistosomiasis in China. In addition，these retrospective investigations provide reliable evidence for revis? ing the Criteria of Schistosomiasis Control and Elimination，and for the more accurate and scientific assessment of the effec? tiveness of schistosomiasis control in China. Related Articles | Metrics | Comments（0）

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Effect of ditching for drain on control of Oncomelania hupensis snail in beaches of Dongting Lake WEI Wang-Yuan, BU Kai-Ming, WEI Kai-Lin, LUO Zhi-Hong, REN Guang-Hui, CHEN Xiang-Lin, YI Jian-Min, LIU Yu, XIANG Yang, TANG Ke-Wen, YAN Jian-Hui, XIA Meng, DING Liang, LU Xian-Jiang, NIE Dong-Song, LI Yuan Chinese Journal of Schistosomiasis Control    2015, 27 (3): 241-.   DOI: 10.16250/j.32.1374.2014133 Abstract （837）      PDF（pc） （2664KB）（112717）       Knowledge map    Save Objective Objective To evaluate the effect of ditching for drain on the control of the breed of Oncomelania hupensis snails in beaches of Dongting Lake. Methods Methods From November，2009 to November，2012，an O. hupensis snail infested beach of the Yueyang jail and an O. hupensis snail infested beach of Junshan District were selected as research fields in the eastern Dongting Lake area，and the former，as the intervention field，was performed with the ditching for drain by excavators and the latter，as the control field，was not. Results Results Before the project implemented，the average soil moisture contents on the beaches in dry seasons of the two fields were both about 35.56%. After the project implemented，in the intervention field，the average soil mois? ture content was 26.53% which was significantly lower than that（35.56%）in the control field（F = 6.53，P < 0.05） . The under? ground water levels in different heights in the intervention field were lower than those in the control field（ χ2 = 33.33，P < 0.05） . Before the project implemented，the natural death rates of the snails were 0.98% and 0.89% in the two research fields re? spectively（P > 0.05），and after the project implemented（in 2012），no adult and young snails were found in the interventional field，but in the control field，the average densities of living snails and young snails were 29.37 snails/0.1 m2 and 213±108.45 snails/0.1 m2 respectively. Conclusion Conclusion The intervention of ditching for drain can decrease the soil moisture contents quickly and change the ecological condition， therefore， can control the breed of O. hupensis snails in the beaches of Dongting Lake. Related Articles | Metrics | Comments（0）

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Effectiveness of integrated schistosomiasis control strategy in marshlands of Qixia District, Nanjing City ZHANG Ke, LIU Ning, HOU Kai, HOU Ning, GONG Yun-Hua, ZHANG Qiu-Ping, YE Jia-Ming, WANG Biao, SUN Ji-Jiang Chinese Journal of Schistosomiasis Control    2015, 27 (4): 428-.   DOI: 10.16250/j.32.1374.2015042 Abstract （771）      PDF（pc） （1540KB）（111824）       Knowledge map    Save Objective Objective To evaluate the effectiveness of integrated schistosomiasis control strategy in marshlands of Qixia Dis? trict from 2004 to 2013. Methods Methods The endemic situation and integrated control data of schistosomiasis in Qixia District from 2004 to 2013 were collected，and the morbidity and Oncomelania hupensis snail status before and after the implementation of in? tegrated schistosomiasis control strategy were compared. Results Results Following 10?year integrated schistosomiasis control，the hu? man schistosome infection rate gradually decreased in Qixia District，and no infection was detected since 2007. A gradual reduc? tion was observed in the infection rate of domestic animals，and all bovine was eliminated from the regions along the Yangtze Riv? er since 2006. In addition，the snail area and the density of living snails in 2013 reduced by 42.25% and 82.56% as compared to those in 2004，and no infected snails were found since 2009. In 2010，the district achieved schistosomiasis transmission control. Conclusion Conclusion The integrated schistosomiasis control strategy is effective to accelerate schistosomiasis control process and achieve the criteria of schistosomiasis transmission control rapidly. Related Articles | Metrics | Comments（0）

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Impact of implementation of Three Gorges Project on schistosomiasis endemic situation in Hubei Province CHEN Yan-Yan, CAI Shun-Xiang, XIAO Ying, CHAN Xiao-Wei, ZHANG Juan, LIU Jian-Bing Chinese Journal of Schistosomiasis Control    2014, 26 (5): 498-.   Abstract （705）      PDF（pc） （1843KB）（111767）       Knowledge map    Save Objective Objective To understand the change of hydrological regime in the Yangtze River and schistosomiasis endemic situation after the implementation of Three Gorges Project in Hubei Province. Methods Methods The data of hydrological regime of the Yangtze River，schistosomiasis epidemic situation，and Oncomelania hupensis snail status were collected and analyzed in Hu? bei Province from 2002 to 2012. Results Results After the implementation of the Three Gorges Project in 2003，the water level of the Yangtze River slightly rose from January to March，the average water level in May and August both reduced compared with that in 2002，and the time of water withdrawal was moved up. The endemic situation of schistosomiasis showed a decline tendency in areas along the Yangtze River in Hubei Province. The positive rate of serological tests in the residents and the Schistosoma ja? ponicum infection rate in bovine decreased by 2.97% and 92.64% respectively. The numbers of human and bovine infected with S. japonicum decreased by 48.35% and 94.48%，respectively. Conclusion Conclusion After the implementation of the Three Gorges Proj? ect，t the schistosomiasis endemic situation shows a decline tendency in the areas along the Yangtze River in Hubei Province，but the long?term monitoring still need to be carried out. Related Articles | Metrics | Comments（0）

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Surveillance of schistosomiasis epidemic situation after its transmission interrupted in Lufeng County, Yunnan Province HUA Ming-Gui, JIN Hua-Zhong, LIU Jian-Hua, DUAN Hong-Mei, XU Xin-Ming Chinese Journal of Schistosomiasis Control    2015, 27 (4): 416-.   DOI: 10.16250/j.32.1374.2015020 Abstract （748）      PDF（pc） （1551KB）（109062）       Knowledge map    Save Objective Objective To investigate the schistosomiasis epidemic situation changes after its transmission interrupted in Lufeng County in 1986，so as to provide the evidence for formulating the interventions for schistosomiasis elimination. Meth Meth? ? ods ods The surveillance of Oncomelania hupensis snail was performed by the systematic sampling，environmental sampling and special environmental comprehensive survey methods. The surveillance of human population was carried out by the serological screening method，and the positives were re ? examined with the stool hatching method. The surveillance of livestock was per? formed by the plastic cup of pipe jacking hatching method. Results Results The living snails were detected in Lufeng County from 1987 to 2007 except in 1988 and 1994. The two import buffalo infected with schistosomes were detected in 2001 and no local infected livestock were found. Since 2004，the comprehensive measures，including the social control strategy and survival snail elimina? tion，were carried out，and no snails were detected and no schistosome infected persons or livestock were found for 7 consecu? tive years since 2008. Conclusions Conclusions The achievement of schistosomiasis transmission interrupted has been consolidated in Lufeng County，but most of the historical snail environments have not been modified and there are still snail breeding conditions. Therefore，we should continue to carry out the snail surveillance. Related Articles | Metrics | Comments（0）

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Research of preferences and security management of tourists in Poyang Lake based on schistosomiasis prevention FENG Shu-Hua Chinese Journal of Schistosomiasis Control    2015, 27 (2): 192-.   DOI: 10.16250/j.32.1374.2014223 Abstract （876）      PDF（pc） （2255KB）（107825）       Knowledge map    Save Objective Objective To discuss the prevention of schistosomiasis in tourism of lake region. Methods Methods The seasonal distri? bution of tourism activities and spatial distribution of scenic spots，as well as the coupling between space and temporal of Onco? melania snail distribution and the transmission time of schistosomiasis in Poyang Lake region were analyzed. The travel prefer? ence of schistosomiasis susceptible population was surveyed by questionnaires and interviews. Results Results There were couplings of space and temporal between tourism activities in Poyang Lake region and transmission time of schistosomiasis as well as space distribution of snails，respectively. The most popular tourism items were Shuishangrenjia（overwater household）and fishing folk culture with property of participation and experience. Conclusion Conclusion The suggestion is to establish health records of tourists，car? ry out health education of schistosomiasis， and enhance the management of tourism and activities of tourists. Related Articles | Metrics | Comments（0）

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Analysis of endemic changes of schistosomiasis in China from 2002 to 2010 WANG Qiang, XU Jing, ZHANG Li-Juan, ZHENG Hao, RUAN Yao, HAO Yu-Wan, LI Shi-Zhu, ZHOU Xiao-Nong Chinese Journal of Schistosomiasis Control    2015, 27 (3): 229-.   DOI: 10.16250/j.32.1374.2015080 Abstract （502）      PDF（pc） （3188KB）（107118）       Knowledge map    Save Objective Objective To provide the reference for schistosomiasis control through analyzing the changes of endemic status of schistosomiasis in China in recent years. Methods Methods The annual data of schistosomiasis prevention and control from 2002 to 2012 were collected, and the descriptive analysis was conducted to describe the changes of schistosomiasis endemic status. Re Re? ? sults sults Sichuan, Yunan and Jiangxi provinces reached the criteria of transmission controlled from 2002 to 2010 while Hubei, Hu? nan, Jiangxi and Anhui provinces reached the criteria of infection controlled in 2008. The number of counties where the trans? mission of schistosomiasis was controlled decreased from 110 in 2002 to 80 in 2010. The numbers of estimated schistosomiasis cases and reported acute cases fell from 810.4 thousands and 913 in 2002 to 325.8 thousands and 43 in 2010, respectively, and they were reduced by 59.79% and 95.40% respectively. The number of infected bovine went down from 23 199 in 2002 to 7 173 in 2010, with a fall of 69.03%. However, the Oncomelania hupensis snails breeding areas kept in 3.7 to 3.8 billion m2 and among which, 125 million m2 areas were newly discovered in non?endemic areas during the nine years. In 2010, 90% of schistosomiasis cases, acute cases, infected bovine, and snail breeding areas were concentrated in 5 provinces, especially in the Dongting Lake and Poyang Lake areas and the regions along the Yangtze River. Conclusions Conclusions The epidemic of schistosomiasis decreased sig? nificantly from 2002 to 2010. The lake regions are the key and tough areas for schistosomiasis prevention and control. To consoli? date the achievements, the surveillance and case management need to be strengthened as the extension of snail breeding areas and acute cases reported from other places becomes common. Related Articles | Metrics | Comments（0）

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Eradication of Schistosomiasis: a New Target and a New Task for the National Schistosomiasis Control Porgramme in the People's Republic of China LEI Zheng-Long, ZHOU Xiao-Nong Chinese Journal of Schistosomiasis Control    2015, 27 (1): 1-.   DOI: 10.16250/j.32.1374.2015036 Abstract （882）      PDF（pc） （2362KB）（105759）       Knowledge map    Save The achievements for the national schistosomiasis control programme in the People’s Republic of China over the last 6 decades were reviewed， with an emphasis on the status and challenges to accomplish the tasks of “Workplan for the Mid? and Long?term of National Schistosomiasis Control Programme from 2004 to 2015”. Four features of current national schistosomiasis control programme were identified in the new stage. First， the high prevalence areas have been shrunk， but few regions are still at the risks of schitosomiasis rebounding. Second， large areas with low prevalence of schistosomiasis will remain for a long time， so that the disease surveillance will be a long?term task. Third， more notable places will be in the high risk areas where more activities of human and livestock occurred， so that it is essential to implement the integrated control measures in those high risk areas. Fourth， the technologies using in the schistosomiasis eradication programme are delayed as expected， and more needs to accelerate the R&D programmes. It was recommended that sustained implementation of integrated control strategy with more emphasis on control of infectious sources has to be strengthened through enhanced regulation performance in addition to the aforementioned notifications， in order to eradicate schistosomiasis in a response to the newly formulated target of “making the ‘God of Plague’ to be sweep away from the history， and retuning the clear land/water and happy/healthy life to the people”. Related Articles | Metrics | Comments（0）

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Investigation of theoretical knowledge on schistosomiasis prevention and control among professionals in county level in Hunan and Hubei provinces ZHANG Li-Juan, ZHU Rong, XU Jing, LI Shi-Zhu Chinese Journal of Schistosomiasis Control    2015, 27 (3): 246-.   DOI: 10.16250/j.32.1374.2015055 Abstract （663）      PDF（pc） （1997KB）（103341）       Knowledge map    Save Objective Objective To understand the knowledge level on schistosomiasis prevention and treatment among professionals of schistosomiasis endemic counties in Hunan and Hubei provinces，so as to provide the basis for the ability construction of schistosomiasis control institution. Methods Methods The theoretical test was applied to investigate the mastering situation on schistoso? miasis prevention and control among professionals of 12 selected schistosomiasis endemic counties in Hunan and Hubei provinc? es，and the results were analyzed statistically. Results Results Ninety?six professionals were surveyed. The average score was 66.94± 11.53，in the range of 34?91，and the pass rate was 75.00%. The scoring rates of the knowledge points of the test and treatment of schistosomiasis，snail survey and killing as well as basic knowledge and laws and regulations about schistosome were 68.69%，70.54% and 73.19%，respectively. On the knowledge points of the test and treatment of schistosomiasis and basic knowledge and laws and regulations about schistosome，the differences among different education backgrounds were significant （F = 3.337，4.793，both P < 0.05），and the scores were higher in professionals with higher diploma. In the scores，there were no statistical differences between or among different genders，age groups，professional titles or specialties（all P > 0.05） . Con Con? ? clusion clusion The overall knowledge level on schistosomiasis prevention and treatment of the professionals from 12 schistosomiasis endemic counties in Hunan and Hubei provinces is low. Therefore， the learning of relative knowledge should be strengthened. Related Articles | Metrics | Comments（0）

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Academic influence of institutes in field of schistosomiasis control and research in China YAO Jia-Wen, GIA Tie-Wu, GUAN Ya-Yi, ZHOU Xiao-Nong Chinese Journal of Schistosomiasis Control    2014, 26 (3): 238-.   Abstract （715）      PDF（pc） （1313KB）（100276）       Knowledge map    Save Objective To assess the academic influence of schistosomiasis control and research institutions in China. Meth? ods The papers（including original articles and reviews）pertaining to schistosomiasis in Science Citation Index Expanded （SCIE）of Web of Science（WOS）during the period from 2002 to 2012 were searched. The number of published papers，h index and citation frequencies of the papers of Chinese institutes and authors were analyzed by a bibliometric method，and the academic influences of the institutes and authors were assessed according to the number of published papers and h index. In addition，the scientific knowledge network map was plotted by using the CiteSpace II software to analyze the inter?institution academic collabora? tion network. Results From 2002 to 2012，totally 610 papers pertaining to schistosomiasis were published by Chinese scholars， accounted for 16.7% of the published papers in global，and the quantity increased year by year. The number of published papers and h index of the National Institute of Parasitic Diseases（NIPD），China Center for Disease Control and Prevention（China CDC） were 114 and 27，respectively，both of which were ranked at the first position among all the Chinese institutes，and in the academ? ic collaboration network，the NIPD played a central and dominate part. Xiao?Nong Zhou with the h index of 17 became the out? standing academic leader in the research field of schistosomiasis control. Conclusions Both number of published papers in SCIE and h index of the Chinese institutes for schistosomiasis control are far inferior to the leading institutions in the world. It suggests that when strengthening the research and control of schistosomiasis，we should pay an attention to the output and sharing of the control experience and achievements. Related Articles | Metrics | Comments（0）

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Endemic status of schistosomiasis in People's Republic of China in 2013 LEI Zheng-Long, ZHENG Hao, ZHANG Li-Juan, ZHU Rong, XU Zhi-Min, XU Jing, FU Qing, WANG Qiang, LI Shi-Zhu, ZHOU Xiao-Nong Chinese Journal of Schistosomiasis Control    2014, 26 (6): 591-.   Abstract （789）      PDF（pc） （4538KB）（52846）       Knowledge map    Save This report presented the endemic status of schistosomiasis in the People's Republic of China at national level in 2013. By the end of 2013，there are 184 943 schistosomiasis japonica cases. Meanwhile，nine acute cases were reported，and 4 cases reduced compared with that of 2012. A total of 29 796 advanced cases were reported；while 911 cases were determined as advanced cases and 1 700 cases were dead in 2013. Nationally，there were around 365 467.99 hm2 Oncomelania snail infested areas in total and 9.25 hm2 of them habituated infected snails in 2013. There were 287.28 hm2 of snail infested areas found in non ?endemic areas historically. Moreover，962 065 cattle were estimated to be raised in endemic regions and 633 cattle were deter? mined as positive by stool examinations. The data showed that the endemicity of schistosomiasis in China decreased further. How? ever，challenges exist to reach the aims of the medium and long term national program. Further control and effective surveillance need to be strengthened as the endemicity of schistosomiasis is unstable in the areas after schistosomiasis transmission under con? trol or interruption. Related Articles | Metrics | Comments（0）

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Geographical and temporal weighted regression model and its application in epidemiology: A review WANG Zhe, LIU Lu, YANG Kun Chinese Journal of Schistosomiasis Control    2023, 35 (2): 199-.   Abstract （1481）      PDF（pc） （1050KB）（21351）       Knowledge map    Save Geographical and temporal weighted regression (GTWR) model is a local regression linear model, which indirectly reflects the spatio⁃temporal non⁃stationary characteristics of the study data by calculating the trends for changes in parameters with space and time. Recently, GTWR model has become one of the hot topics in the study on spatio⁃temporal heterogeneity of diseases. This review summarizes the basic principles and study methods of the GTWR model, and describes the applications of this model in epidemiology. Related Articles | Metrics | Comments（0）

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Advances in research of protein kinase A in parasites: a review FAN Jun-Jie, LI Kai, TAN Qing-Qing, CAO Wen-Qiao, YE Bin Chinese Journal of Schistosomiasis Control    2020, 32 (5): 538-.   Abstract （759）      PDF（pc） （921KB）（15099）       Knowledge map    Save Protein kinase A (PKA) is an important intracellular substance that regulates substance metabolism and biological functions, which exerts a wide range of biological effects through phosphorylation of specific serine/threonine residues in specific proteins. PKA plays an important role in the cAMP signaling pathway, and is involved in various life activities of parasites. Therefore, investigating the role of PKA in the life activities of parasites may provide insights into the development of novel anti?parasitic targets. The review mainly describes the structure and function of PKA and its role in life activities of parasites. Related Articles | Metrics | Comments（0）

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Prevalence and fundamental researches of prevention and treatment of toxoplasmosis in China: an overview SHEN Ji-Long, YU Li Chinese Journal of Schistosomiasis Control    2019, 31 (1): 71-76.   Abstract （1497）      PDF（pc） （1002KB）（10481）       Knowledge map    Save Toxoplasma gondii is an important zoonotic pathogen and its infection has a significant impact on human health and animal husbandry. This review presents the research progresses in the epidemic, genotype, pathogenicity, diagnosis, treatment and vaccine development of Toxoplasma and toxoplasmosis in China, so as to provide the reference for the study of the pathogen and the disease in the country. Related Articles | Metrics | Comments（0）

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The role of sinusoidal endothelial cells in liver injury: a review JIANG Tingting, HU Yuan, CAO Jianping Chinese Journal of Schistosomiasis Control    2023, 35 (1): 92-.   Abstract （984）      PDF（pc） （958KB）（10442）       Knowledge map    Save Liver sinusoidal endothelial cells (LSECs) locate on the surface of hepatic sinusoids. As the first line of defense between the liver and blood, LSECs are the most abundant non-parenchymal cells in the liver. Under physiological conditions, LSECs may induce liver immune tolerance through participating in substance transport and metabolic waste removal, thereby maintaining liver homeostasis, and under pathological conditions, LSECs may promote liver immune response via antigen presentation. LSECs have been found to play a crucial regulatory role in maintaining the balance between liver regeneration and liver fibrosis. This article reviews the progress of researches on LSECs functions, LSECs changes in liver injury, signal pathways associated with regulation of LSECs functions, and the interaction between LSECs and other types of cells in the liver, aiming to elucidate the function of LSECs and their roles in liver diseases Related Articles | Metrics | Comments（0）

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Discovery and distribution of and response to arbovirus in China over the past seven decades XIA Han, YUAN Zhiming Chinese Journal of Schistosomiasis Control    2023, 35 (5): 427-436,450.   Abstract （1018）      PDF（pc） （1541KB）（9544）       Knowledge map    Save Arbovirus is a group of virus transmitted by blood⁃sucking arthropod bites, which infects both arthropods and vertebrates. More than 600 arboviruses have been characterized worldwide until now, including 65 highly pathogenic viruses, which pose a high threat to public health. The risk of arbovirus transmission is increasing due to climate change, international trade and urbanization. The review summarizes the discovery and distribution of emerging and reemerging arboviruses and novel arboviruses with potential pathogenic risks, and proposes responses to the arbovirus transmission risk, so as to provide insights into the research and management of arboviruses and arthropod⁃borne infectious diseases in China. Related Articles | Metrics | Comments（0）

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Mechanism of hepatic fibrosis associated with Echinococcus: a review ZHANG Ren⁃jie, PANG Hua⁃sheng, LI Jing⁃zhong, LUO Zhao⁃hui, AI Lin, SONG Peng, CAI Yu⁃chun, LU Yan, MO Xiao⁃jin, CHEN Mu⁃xin , CHEN Jia⁃xu Chinese Journal of Schistosomiasis Control    2022, 34 (6): 646-.   Abstract （645）      PDF（pc） （1023KB）（8558）       Knowledge map    Save Echinococcosis is a zoonotic parasitic disease caused by Echinococcus infections, and this disorder may cause fibrosis of multiple vital organs, which may further progress into cirrhosis. Early⁃stage hepatic fibrosis is reversible, and unraveling the mechanisms underlying hepatic fibrosis induced by Echinococcus infections is of great significance for the prevention and treatment of early⁃stage hepatic fibrosis. Recently, the studies pertaining to hepatic fibrosis associated with Echinococcus infections focus on cytokines and immune cells. This review summarizes the advances in the mechanisms underlying host immune cells⁃ and cytokines⁃mediated hepatic fibrosis in humans or mice following Echinococcus infections. Related Articles | Metrics | Comments（0）

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Status and control of common food⁃borne parasitic diseases in China: a review HUANG Ji⁃Lei, WANG Yao, ZHOU Xia Chinese Journal of Schistosomiasis Control    2021, 33 (4): 424-.   Abstract （2823）      PDF（pc） （1011KB）（8556）       Knowledge map    Save Food⁃borne parasitic diseases include meat⁃borne, fish⁃borne, plant⁃borne, water⁃borne, mollusk⁃borne and freshwater crustacean⁃borne parasitic diseases. The review summarizes the current status and control of 6 major food⁃borne parasitic diseases in China, including clonorchiasus, paragonimiasis, Taenia solium taeniasis, toxoplasmosis, trichinellosis and angiostrongyliasis, aiming to increase the understanding of food⁃borne parasitic diseases and provide insights into the development of the control strategy for food⁃borne parasitic diseases. The transmission of food⁃borne parasitic diseases are predominantly associated with diet, and neither eating raw nor semi⁃cooked food is the most effective measure to prevent the development of food⁃borne parasitic diseases. Related Articles | Metrics | Comments（0）

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Artificial intelligence technology enables ultrasonography in precision diagnosis and treatment of liver diseases ZHOU Bo⁃yang, SHI Yi⁃lei, GUO Le⁃hang, MOU Li⁃chao, ZHU Xiao⁃xiang, ZHAO Chong⁃ke Chinese Journal of Schistosomiasis Control    2022, 34 (5): 458-.   Abstract （1634）      PDF（pc） （1084KB）（7704）       Knowledge map    Save Liver disease is one of the major problems affecting human health. Ultrasound plays an important role in diagnosis and treatment of diffuse and focal liver diseases. However, conventional ultrasound evaluation is subjective and provides limited information. Artificial intelligence (AI) technology may supplement the disadvantages of conventional ultrasound and has been widely used in the field of ultrasound in liver diseases. To date, remarkable progress has been achieved for the use of AI technology in the diagnosis, assessment of therapeutic efficacy and prognosis prediction of liver diseases. This paper reviews the research progress of ultrasound image⁃based AI technology in the diagnosis and treatment of diffuse and focal liver diseases. Related Articles | Metrics | Comments（0）

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Progress of research on ovicidal and larvicidal activity against parasites in vitro LI Wei, LIANG You-Sheng Chinese Journal of Schistosomiasis Control    2009, 21 (3): 231-234.   Abstract （837）      PDF（pc） （3747KB）（6832）       Knowledge map    Save Related Articles | Metrics | Comments（0）

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Progress of researches on global prevalence of Blastocystis hominis human infections and its subtypes ZHANG Fu-Qiang, WANG Pei, FENG Xia, MI Qiu-Min, MEI Xue-Fang, ZHANG Zhen-Chao, LI Xiang-Rui, WANG Shuai Chinese Journal of Schistosomiasis Control    2021, 33 (1): 84-.   Abstract （1233）      PDF（pc） （1360KB）（6784）       Knowledge map    Save Blastocystis hominis is a parasite that parasitizes in the intestines of humans and animals, and is closely related to a variety of gastrointestinal diseases such as abdominal pain and diarrhea. B. hominis is distributed worldwide, and the prevalence of B. hominis infections and dominant subgenotypes vary in countries and in regions from the same country. This paper reviews the global prevalence of B. hominis human infections, its subtypes and geographical distribution, so as to provide insights into the understanding of the global epidemiology of B. hominis and the management of B. hominis infections. Related Articles | Metrics | Comments（0）

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Research and application of epitope ZHANG Wei, YU Chuan-Xin Chinese Journal of Schistosomiasis Control    2012, 24 (1): 99-103.   Abstract （876）      PDF（pc） （1150KB）（6419）       Knowledge map    Save Epitope is the basic functional motif of antigen inducing immune response. In immunological research and medical practice, the identification and selection of epitopes are the key points. This paper reviews the current progress of the epitope re? search and its application in disease diagnosis, vaccine research, disease treatment and other fields. Related Articles | Metrics | Comments（0）

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Advances in research on aquaporins in medical helminthes WANG Fen, YE Bin Chinese Journal of Schistosomiasis Control    2020, 32 (5): 542-.   Abstract （540）      PDF（pc） （1792KB）（6369）       Knowledge map    Save Aquaporins (AQPs) are a class of membrane intrinsic proteins in medical helminthes that specifically mediate the transmembrane transport of water or other solute molecules. Previous studies have demonstrated that AQPs play a critical role in promoting the transmembrane transport of water, osmoregulation, uptake of nutrients, release of toxic metabolic products and transport of antiparasitic drugs, which may serve as promising vaccine candidates and drug targets for parasitic diseases. This review describes the structural characteristics of AQPs in medical helminthes, and discusses the feasibility of these AQPs as anti-helminth vaccine candidates and drug targets, so as to provide insights into the development of novel vaccines and drugs against parasitic diseases. Related Articles | Metrics | Comments（0）

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Advances in research of dihydroartemisinin against parasitic diseases LI Hong-Jun, WANG Wei, LIANG You-Sheng Chinese Journal of Schistosomiasis Control    2011, 23 (4): 460-464.   Abstract （1297）      PDF（pc） （1021KB）（5461）       Knowledge map    Save Dihydroartemisinin, the main metabolite of artemisinin and of two artemisinin derivatives, artemether and artesunate, is a broad-spectrum anti-parasitic drug. The present paper systematically reviews the advances in research of dihydroartemisinin against malaria, Schistosoma, Pneumocystis, Toxoplasma, Trichomonas vaginalis, Leishmania, Giardia lamblia. Related Articles | Metrics | Comments（0）

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Effects of five Chinese herbs on human demodicid mites in vitro PAN Yi-ning， ZHAO Ying， ZHAO Ru-juan，YANG Xue-rong，LI Tian-ci，HU Ting-ting，YANG Yan，ZHAO Jin-hong Chinese Journal of Schistosomiasis Control    2019, 31 (3): 301-.   Abstract （842）      PDF（pc） （1073KB）（5305）       Knowledge map    Save Objective To research the effects of five Chinese herbs of Artemisia argyi， Chimonanthus praecox， Agastache rugosa， pine needles and Osmamthus fragrans on human demodicid mites in vitro. Methods The human demodicid mites were acquired with the cellophane tape method. The ethanol heat reflux extractions were carried out on the 5 kinds of Chinese herbs to be studied and Stemona sessilifolia as the positive control， so as to get the herbal extracts. Next， the drug administration was carried out to the demodicid mites， and the inhibitory or killing effects of the 6 kinds of Chinese herbs above mentioned on the vermiform mites were observed under a microscope. It was considered to be dead when the bodies of the demodicid mites stopped moving. Besides， the duration from drug administration to death of the vermiform mites was recorded， and the data was analyzed by SPSS 17.0. Results Artemisia argyi， Chimonanthus praecox and Agastache rugosa could effectively inhibit and kill human demodicid mites. The effect of Artemisia argyi and Agastache rugosa was similar to the effect of Stemona sessilifolia， and the effect of Chimonanthus praecox was weaker than Stemona sessilifolia’s effect. Among them， Agastache rugosa took a relatively short time （[4.60±1.66]） min and Osmamthus fragrans took the longest time （[114.65±80.14]） min to Demodex folliculorum； Whereas， Artemisia argyi took the shortest time （[3.56±1.92]） min and Osmamthus fragrans took the longest time （[194.24±134.96]） min to Demodex brevis. Conclusions The effects of Artemisia argyi and Agastache rugosa on human demodicid mites are similar to that of Stemona sessilifolia. The effects of Chimonanthus praecox and pine needles are weaker than that of Stemona sessilifolia. Osmamthus fragrans has no acaricidal effect. Related Articles | Metrics | Comments（0）

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Epidemiology of pathogenic tick-borne viruses in China: a review#br# #br# MA Jingge, LIU Ning, LIU Ziyan, LIU Quan, WEI Feng, WANG Zedong Chinese Journal of Schistosomiasis Control    2023, 35 (4): 325-330,348.   Abstract （1093）      PDF（pc） （973KB）（5277）       Knowledge map    Save Ticks are obligate, haematophagous arthropods that are distributed across the world, which may transmit more than 200 pathogens, including viruses, bacteria and parasites. A large number of tick species are widespread in China, and their transmitting tick-borne viral diseases pose a great threat to human health in endemic foci. This review describes the epidemiology of common, emerging and potentially pathogenic tick-borne viruses in China, and recommends the assessment of public health significance and pathogenicity of emerging tick-borne viruses using reverse microbial etiology, so as to provide insights into the management of emerging tick-borne diseases in China. Related Articles | Metrics | Comments（0）

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The role of macrophage polarization in parasitic infections: a review CAI Juan, HUANG Lin, WANG Ling-Jun, ZHENG Ming-Hui, LIU Hui Chinese Journal of Schistosomiasis Control    2020, 32 (4): 432-.   Abstract （870）      PDF（pc） （934KB）（5244）       Knowledge map    Save Macrophages are important members of innate immunity and play an extremely important role in the host defense against pathogenic infections, tumors, and allergic diseases. Macrophages have a high degree of plasticity, and may be polarized into classical activated macrophages (M1 macrophages) and alternative activated macrophages (M2 macrophages) under the stimulation of different environments. M1 macrophages are found to promote inflammatory responses, which facilitates the clearance of pathogens, while M2 macrophages may inhibit inflammatory responses, which facilitates the survival and reproduction of pathogens. This review summarizes the role of macrophage polarization in parasitic infections, so as to provide insights into the prevention and treatment of parasitic diseases. Related Articles | Metrics | Comments（0）