Abstract: Ticks are obligate, haematophagous arthropods that are distributed across the world, which may transmit more than 200 pathogens, including viruses, bacteria and parasites. A large number of tick species are widespread in China, and their transmitting tick-borne viral diseases pose a great threat to human health in endemic foci. This review describes the epidemiology of common, emerging and potentially pathogenic tick-borne viruses in China, and recommends the assessment of public health significance and pathogenicity of emerging tick-borne viruses using reverse microbial etiology, so as to provide insights into the management of emerging tick-borne diseases in China.

Key words: Tick, Tick-borne virus, Tick-borne disease, Epidemiology, Reverse microbial etiology

摘要： 蜱是一种呈全球性分布的体外吸血节肢动物，可传播包括病毒、细菌、寄生虫在内的200余种病原。我国蜱种类多、分布广，其传播的病毒性疾病给流行区广大人民群众身体健康造成了严重威胁。本文概述了我国常见、新发及具有潜在致病性的蜱媒病毒流行现状，并建议利用反向病原学研究策略开展新发蜱媒病毒公共卫生意义评估及致病性研究，从而为我国新发蜱传疾病防控提供参考。

关键词: 蜱, 蜱媒病毒, 蜱传疾病, 流行病学, 反向病原学