Abstract: The insecticide resistance is becoming increasingly severe in malaria vectors and has become one of the most important threats to global malaria elimination. Currently, malaria vectors not only have developed high resistance to conventional insecticides, including organochlorine, organophosphates, carbamates, and pyrethroids, but also have been resistant to recently used neonicotinoids and pyrrole insecticides. This article describes the current status of global insecticide resistance in malaria vectors and global insecticide resistance management strategies, analyzes the possible major challenges in the insecticide resistance management, and proposes the response actions, so as to provide insights into global insecticide resistance management and contributions to global malaria elimination.

Key words: Malaria, Elimination, Malaria vector, Anopheles, Insecticide resistance, Resistance management

摘要： 传疟媒介杀虫剂抗性问题日益严峻，已成为全球消除疟疾面临的最重要挑战之一。目前，传疟媒介不仅对有机氯、有机磷、氨基甲酸酯和拟除虫菊酯类等传统杀虫剂产生了高度抗性，而且对近年来新使用的新烟碱类和吡咯类杀虫剂亦产生了抗性。本文对当前全球传疟媒介杀虫剂抗性现状和相关抗性治理策略进行了梳理，并就杀虫剂抗性治理中存在的主要问题进行了分析，提出了下一步应对措施，旨在为全球传疟媒介杀虫剂抗性治理提供科学参考，助力全球消除疟疾。

关键词: 疟疾, 消除, 传疟媒介, 按蚊, 杀虫剂抗性, 抗性治理