Abstract: Objective Objective To understand the impact of niclosamide ethanolamine salt on the Yangtze River wetland creatures， so as to provide an evidence for the environmental impact assessment of the Oncomelania hupensis control measures. Methods Methods Eriocheir sinensis，Procambarus clarkii，freshwater mysis and Bellamya aeruginosa were chosen as the test organisms from the lower reaches of the Yangtze River in Nanjing City，and they were immersed in the different concentrations of niclosamide etha? nolamine salt solution for 24-96 h. The mortality rates and LC50 values were calculated. Results Results There was only 1 death（with a mortality rate of 8.33%）of P. clarkia immersed in niclosamide ethanolamine salt with the concentration of 400 mg/L for 96 h. There was no death of the E. sinensis immersed in niclosamide ethanolamine salt with the concentration of 640 mg/L for 96 h. The LC50 values were 2.170 4，1.303 6，1.013 1 mg/L and 0.720 5 mg/L respectively when the freshwater mysis were immersed in the solution for 24，48，72 h and 96 h. The LC50 values were 1.173 5，0.642 1，0.477 3 mg/L respectively when the B. aeruginosa were immersed in the solution for 24，48，72，96 h. Conclusions Conclusions The impacts of niclosamide ethanolamine salt on the differ? ent wetland creatures are different. E. sinensis and P. clarkii have high resistance to niclosamide ethanolamine salt. However，ni? closamide ethanolamine salt shows heavy toxicity on the freshwater mysis and Bellamya aeruginosa.

Key words: Niclosamide ethanolamine salt；Molluscicide；Wetland organism；Eriocheir sinensis；Procambarus clarkii； Freshwater mysis；Bellamya aeruginosa；Oncomelania snail；Toxicity；Ecological protection

摘要： 目的 目的 了解氯硝柳胺乙醇胺盐对长江湿地生物的影响， 为钉螺控制措施的环境影响评价提供科学依据。 方 方 法 法 选择长江下游南京段中华绒毛蟹、 克氏原螯虾、 淡水糠虾和铜锈环棱螺作为受试生物， 观察不同浓度氯硝柳胺乙醇 胺盐浸泡后受试生物的死亡情况， 计算受试生物死亡率和LC50。 结果 结果 克氏原螯虾在氯硝柳胺乙醇胺盐400 mg/L浓度 浸泡96 h仅死亡1只， 死亡率为8.33%； 中华绒毛蟹在氯硝柳胺乙醇胺盐640 mg/L浓度浸泡96 h无死亡； 氯硝柳胺乙醇胺 盐对淡水糠虾24、 48、 72、 96 h的LC50分别为2.170 4、 1.303 6、 1.013 1、 0.720 5 mg/L； 对铜锈环棱螺24、 48、 72 h的LC50分别 为1.173 5、 0.642 1、 0.477 3 mg/L。 结论 结论 氯硝柳胺乙醇胺盐对湿地生物影响不同， 中华绒毛蟹和克氏原螯虾对氯硝柳 胺乙醇胺盐有较强的耐受性； 氯硝柳胺乙醇胺盐对铜锈环棱螺和淡水糠虾毒性较大。

关键词: 氯硝柳胺乙醇胺盐； 杀螺剂； 湿地生物； 中华绒毛蟹； 克氏原螯虾； 淡水糠虾； 铜锈环棱螺； 钉螺； 毒性； 生态保 护