关键词: 土源性线虫病, 时空分布, 流行趋势, 四川省

Abstract: Objective　To investigate the trends in the prevalence of soil⁃transmitted nematode infections and the spatio⁃temporal distribution characteristics of soil⁃transmitted nematodiasis in Sichuan Province from 2016 to 2021, so as to provide the evidence for formulating the soil⁃transmitted nematodiasis elimination strategy in Sichuan Province. Methods　The soil⁃transmitted nematodiasis surveillance data in Sichuan Province from 2016 to 2021 were collected, and the epidemic trend of soil⁃transmitted nematode infections was identified. The distribution maps of soil⁃transmitted nematode infections in Sichuan Province were plotted to identify their spatial distribution characteristics. In addition, the spatial clusters of soil⁃transmitted nematode infections were detected using globa and local spatial autocorrelation analyses. Results　The prevalence of soil⁃transmitted nematode infections appeared a decline with time in Sichuan Province from 2016 to 2021 ([χ2] = 400.24, P < 0.01). Global spatial autocorrelation analysis identified positive spatial autocorrelations in the prevalence of soil⁃transmitted nematode infections (Moran’s I = 0.322, Z = 16.293, P < 0.01), hookworm infections (Moran’s I = 0.425, Z = 21.290, P < 0.01), Ascaris lumbricoides infections (Moran’s I = 0.102, Z = 5.782, P < 0.01) and Trichuris trichiura infections (Moran’s I = 0.084, Z = 6.873, P < 0.01). Local spatial autocorrelation analysis showed that the high⁃high clusters of soil⁃transmitted nematode infections were mainly located in 37 counties (cities, districts) of Sichuan Province, and the high⁃high clusters of hookworm, A. lumbricoides and T. trichiura infections were mainly identified in 39 counties (cities, districts) in mountainous areas around Sichuan Basin and hilly areas, 9 counties (cities, districts) in mountainous areas in southwestern Sichuan Province, and 8 counties (cities, districts) in mountainous areas in southwestern Sichuan Province, respectively. Conclusions　The prevalence of soil⁃transmitted nematode infections appeared a tendency towards a decline in Sichuan Province from 2016 to 2021, which showed spatial clusters. The management of soil⁃transmitted nematodiasis requires to be reinforced in high⁃risk areas of Sichuan Province with adaptations to local epidemiological features.

Key words: Soil?transmitted nematodiasis, Spatio?temporal distribution, Epidemic trend, Sichuan Province