Abstract: Objective　To investigate the prevalence of Clonorchis sinensis human infections in Congjiang County, Guizhou Province in 2023, so as to provide insights into formulation of the clonorchiasis control strategy. Methods　Congjiang County was divided into eastern, western, southern, northern and central areas according to the geographical locations, and one township was randomly sampled from each area. Then, each administrative village was randomly sampled from each township, and 200 permanent residents over 3 years of age were randomly sampled from each village. Participants' stool samples were collected for detection of C. sinensis eggs with the Kato⁃Katz technique (two slides for each stool sample), and the prevalence and intensity of C. sinensis infections were calculated. In addition, the risk factors of clonorchiasis were identified among participants using a questionnaire survey. Results　A total of 1 001 residents were included, and the prevalence of C. sinensis infections was 16.28% (163/1 001), with mild infections as the predominant category of infection intensity [73.01% (119/163)]. The prevalence rates of C. sinensis human infections were 30.50% (61/200), 1.50% (3/200), 30.35% (61/201), 12.50% (25/200), and 6.50% (13/200) at five survey sites, respectively ([χ2] = 107.03, P < 0.05), and there was a significant difference in the prevalence of C. sinensis infections between men [22.44% (112/499)] and women [10.16% (51/502)] ([χ2] = 27.71, P < 0.05). The prevalence of C. sinensis infections was relatively high among participants at ages of 60 to 70 years [26.14% (23/88)], public servants [46.15% (6/13)], and Han ethnic participants [33.33% (5/15)]. The prevalence of C. sinensis infections was higher among participants with a habit of consuming raw or undercooked freshwater fish and shrimp [22.06% (90/408)] than among those without the habit [12.31% (73/593)] ([χ2] = 16.85, P < 0.05), and there was no significant difference in the prevalence of C. sinensis infections between participants with [13.99% (41/293)] and without separation of raw and cooked chopping boards [17.23% (122/708)] ([χ2] = 1.59, P > 0.05). In addition, the prevalence of C. sinensis infections was 8.70% (2/23) and 16.46% (161/978) among participants with and without fever complicated by discomfort in the right upper abdomen during the past half year ([χ2] = 0.99, P > 0.05). Conclusions　The prevalence of C. sinensis human infections was high in Congjiang County, Guizhou Province in 2023, and infections predominantly occurred among young and middle⁃aged men. Intensified health education among high⁃risk residents and alteration of dietary habits of consuming raw or undercooked freshwater fish or shrimp are recommended to reduce the prevalence of C. sinensis human infections.

Key words: Clonorchis sinensis, Infection, Current prevalence, Congjiang County

摘要： 目的　了解2023年贵州省从江县人群华支睾吸虫感染情况，为制定该县华支睾吸虫病防控策略提供科学依据。方法　将从江县按地理方位划分为东、西、南、北、中5个片区，每个片区随机抽取1个乡（镇）的1个行政村作为调查点，每村选取200名3岁以上常住居民作为调查对象。收集调查对象粪便样本，采用改良加藤厚涂片法（1粪2检）检测华支睾吸虫虫卵，计算感染率及感染度。同时，对调查对象开展问卷调查以了解华支睾吸虫病危险因素。结果　本研究共调查1 001人，检出华支睾吸虫感染者163人，感染率为16.28%（163/1 001），感染程度以轻度感染为主［73.01%（119/163）］。5个调查点华支睾吸虫感染率分别为30.50%（61/200）、1.50%（3/200）、30.35%（61/201）、12.50%（25/200）、6.50%（13/200），差异有统计学意义（[χ2] = 107.03，P < 0.05）。男、女性华支睾吸虫感染率分别为22.44%（112/499）和10.16%（51/502），差异有统计学意义（[χ2] = 27.71，P < 0.05）。60～< 70岁年龄组［26.14%（23/88）］、公职人员［46.15%（6/13）］、汉族［33.33%（5/15）］等调查对象华支睾吸虫感染率相对较高。有、无生食或半生食淡水鱼虾习惯者华支睾吸虫感染率分别为22.06%（90/408）和12.31%（73/593），差异有统计学意义（[χ2] = 16.85，P < 0.05）；生熟砧板分开、不分开使用者华支睾吸虫感染率分别为13.99%（41/293）和17.23%（122/708），差异无统计学意义（[χ2] = 1.59，P > 0.05）；近半年有、无发热伴右上腹部不适者华支睾吸虫感染率分别为8.70%（2/23）和16.46%（161/978），差异无统计学意义（[χ2] = 0.99，P > 0.05）。结论　贵州省从江县华支睾吸虫感染率较高，且以中青年男性为主要感染群体。应加强对该县重点人群的健康教育，改变其生食或半生食淡水鱼虾的饮食习惯，以降低华支睾吸虫感染率。  

关键词: 华支睾吸虫, 感染, 流行现状, 从江县