Abstract: Currently, the Global Burden of Disease Study (GBD) is the most comprehensive, systematic, and largest-scale global observational epidemiological project, which measures the national, regional and global mortality and disability of diseases, injuries and risk factors that threaten human health using unified indicators, such as disability-adjusted life year. This review describes the development history, assessment process and methodological advances of GBD, and discusses the impact of GBD on the burden of parasitic diseases, aiming to provide insights into the widespread use of GBD.

Key words: 　Global Burden of Disease Study, Parasitic disease, Burden of disease, Methodology

摘要： 全球疾病负担研究（Global Burden of Disease Study，GBD）是目前最综合、最系统、最大规模的世界性观察流行病学研究项目，采用伤残调整寿命年（disability-adjusted life year，DALY）等一致性指标对威胁人类健康的主要疾病、伤害和危险因素所致的死亡和伤残进行国家、地区和全球水平的人群健康进行综合测量。本文全面介绍了GBD的发展史、评估流程和方法学研究进展及其对寄生虫病疾病负担的影响，从而为GBD方法的推广应用提供参考。

关键词: 　全球疾病负担研究, 寄生虫病, 疾病负担, 方法学