Abstract: Objective　To investigate the prevalence of comorbid depression and anxiety and to evaluate the effect of psychological interventions among schistosomiasis patients in China, so as to provide insights into improvements of psychological health among schistosomiasis patients. Methods　Publications pertaining to comorbid depression and anxiety and psychological interventions among Chinese schistosomiasis patients were retrieved in electronic databases, including CNKI, Wanfang Data, PubMed, Web of Science, and Embase. The prevalence of comorbidity, psychological interventions, and scores for the Self⁃Rating Depression Scale (SDS) and Self⁃Rating Anxiety Scale (SAS) before and after psychological interventions among Chinese schistosomiasis patients were extracted. The prevalence of comorbid depression and anxiety was investigated among Chinese schistosomiasis patients using a meta⁃analysis, and the effect of psychological interventions for depression and anxiety was evaluated. Results　A total of 231 publications were retrieved, and 14 publications that met the inclusion and exclusion criteria were included in the final analysis, including 2 English publications and 12 Chinese publications. Meta⁃analysis showed that the prevalence rates of comorbid depression and anxiety were 61% [95% confidential interval (CI): (48%, 72%)] and 64% [95% CI: (42%, 81%)] among Chinese schistosomiasis patients. Both the SDS [1.45 points, 95% CI: (1.30, 1.60) points] and SAS scores [2.21 points, 95% CI: (2.05, 2.38) points] reduced among Chinese schistosomiasis patients after psychological interventions than before psychological interventions, and the SDS [−0.47 points, 95% CI: (−6.90, −0.25) points] and SAS scores [−1.30 points, 95% CI: (−1.52, −1.09) points] reduced among Chinese schistosomiasis patients in the case group than in the control group. Conclusions　The comorbid anxiety and depression are common among Chinese schistosomiasis patients, and conventional psychological interventions facilitate the improvements of anxiety and depression among schistosomiasis patients.

Key words: Schistosomiasis, Comorbidity, Depression, Anxiety, Psychological intervention, Meta?analysis

摘要： 目的　了解中国血吸虫病患者共病抑郁和焦虑患病率以及使用心理干预治疗的效果，为改善患者心理健康状况提供依据。方法　在中国期刊全文数据库（CNKI）、万方数据资源系统、PubMed、Web of Science、Embase中，检索公开发表的有关中国血吸虫病患者共病焦虑、抑郁，以及心理干预治疗的文献。对文献进行筛选后，提取共病率、心理治疗方法、治疗前后抑郁自评量表（self⁃rating depression scale，SDS）和焦虑自评量表（self⁃rating anxiety scale，SAS）评分等数据，采用meta分析对中国血吸虫病患者抑郁、焦虑共病率进行分析，并评价心理干预方法治疗患者焦虑、抑郁的效果。结果　共检索到231篇文献，最终筛选出符合纳入和排除标准的14篇文献，包括2篇英文文献、12篇中文文献。Meta 分析结果显示，中国血吸虫病患者抑郁共病率为 61% [95%可信区间（confidence interval，CI）： （48%，72%）]，焦虑共病率为64% [95% CI：（42%，81%）]。经心理干预治疗后，血吸虫病患者SDS量表评分 [1.45，95% CI：（1.30，1.60）]、SAS量表评分[2.21，95% CI：（2.05，2.38）]均较治疗前降低，病例组SDS量表评分[−0.47，95% CI （−0.69，−0.25）]、SAS量表评分[−1.30，95% CI：（−1.52， −1.09）]均低于对照组。结论　中国血吸虫病患者共病焦虑及抑郁情绪问题较普遍，临床常用心理干预方法有助于改善血吸虫病患者抑郁和焦虑症状。

关键词: 血吸虫病, 共病, 抑郁, 焦虑, 心理干预, Meta分析