Abstract: Objective Objective To understand the status of Toxoplasma gondii（TOX）infection in childbearing age and pregnant women in Langfang City，Hebei Province. Methods Methods Totally 276 pregnant women and 462 childbearing age women were investi? gated to detect the levels of TOX antibodies with ELISA from March 2013 to June 2015. Results Results The positive rates of Tox?IgG and Tox?IgM were 11.59%（32/276）and 5.43%（15/276）respectively in the pregnant women，and the rates were 8.87% （41/ 462） and 0.87% （4/462）respectively in the childbearing age women，and the positive rate of Tox?IgM of the pregnant women was higher than that of the childbearing age women（χ2 =14.32，P＜0.01） . The positive rate of the right age pregnant women（≤ 35 years）was 10.09%（22/218），and that of the advanced age pregnant woman（＞35 years）was 25.86%（15/58），and the differ? ence was statistically significant（χ2 = 9.81，P＜0.01） . The positive rate of women close contacting with pet was 18.67%（14/ 75），and the rate of women not close contacting with pet was 10.26%（68/663），and there was a statistically significant differ? ence between them（χ2 =4.82，P＜0.05） . Conclusions Conclusions The positive rates of Toxoplasma antibodies are high in childbearing age and pregnant women in Langfang City，Hebei Province，and most of them are silent infection，and the recent infection rate is higher in the latter than that in the former.

Key words: Toxoplasma gondii, Infection, Childbearing age women, Pregnant women, Langfang City, Hebei Province

摘要： 目的 目的 了解河北省廊坊市育龄期妇女及孕妇弓形虫感染状况。方法 方法 以2013年3月至2015年6月在廊坊四院 就诊的276例孕妇和462名育龄期妇女为调查对象， 采用ELISA法进行血清学检测， 以了解弓形虫感染状况。结果 结果 孕 妇弓形虫IgG、 IgM抗体阳性率分别为 11.59% （32/276） 和5.43% （15/276）； 育龄期妇女弓形虫IgG、 IgM抗体阳性率分别为 8.87% （41/462） 和0.87% （4/462）。孕妇IgM抗体阳性率高于育龄期妇女， 差异有统计学意义 （χ2 =14.32， P＜0.01）。适龄 孕妇 （≤ 35岁） 和高龄孕妇 （＞35岁） 弓形虫抗体阳性率分别为10.09% （22/218） 和25.86% （15/58）， 差异有统计学意义 （χ2 = 9.81， P＜0.01）。有、 无宠物密切接触史者弓形虫抗体阳性率分别为18.67% （14/75） 和10.26% （68/663）， 差异有统 计学意义 （χ2 = 4.82， P＜0.05）。结论 结论 廊坊市育龄期妇女与孕妇弓形虫抗体阳性率较高， 多为隐形感染； 孕妇新近感染 率高于育龄期妇女。

关键词: 弓形虫, 感染, 育龄妇女, 孕妇, 廊坊市, 河北省