关键词: 输血传播, 疟疾, 疟原虫, 恶性疟, 金华市

Abstract: This article reports the diagnosis and treatment of a case with transfusion⁃transmitted Plasmodium falciparum malaria. The patient had no history of travel to malaria⁃endemic regions or previous history of infections; however, the case had a history of multiple blood transfusions prior to disease onset. The patient was admitted due to fever of unknown causes. Metagenomic next⁃generation sequencing revealed Plasmodium infection, and P. falciparum malaria was definitively diagnosed following blood smear microscopy and real⁃time fluorescence quantitative reverse transcription PCR (RT⁃qPCR) assay. Epidemiological investigations showed an Ethiopian blood donor with weakly positive rapid diagnostic test (RDT) results. The patient was cured following a 7⁃day treatment with artesunate injection and no recurrence or relapse occurred during the 3⁃month follow⁃up.

Key words: Blood transfusion transmission, Malaria, Plasmodium, Plasmodium falciparum malaria, Jinhua City