中国血吸虫病防治杂志（中英文） ›› 2025, Vol. 37 ›› Issue (6): 569-579.

• 专家共识 •    下一篇

日本血吸虫病肝纤维化超声诊断路径的专家共识

李博1△，李石柱2△，许静2，郭照宇2, 3，吴忠道4，吴海玮5， RICHTER Joachim6，7，宁安8，闻礼永9，张世清10，林丹丹8，杨坤11，华海涌11，孙希4，元艺12，李华忠13，杨米扬4，贺德慧14，曹承斌10，吴斌15，朱龙强15，颜飞雄1，郑茂1，王洪波1，潘舸1，田英1，李俊1，李卫湘1，段娟1，龚纯1，任光辉1，师颖瑞1*，周晓农2* 
  

  1. 1 湖南省血吸虫病防治所（湖南省第三人民医院）、WHO湖区血吸虫病防治合作中心、湖区血吸虫病防治技术区域合作中心、血吸虫病免疫与传播控制湖南省重点实验室、国家血吸虫病临床重点专科（湖南 岳阳 414000）；2 中国疾病预防控制中心寄生虫病预防控制所（国家热带病研究中心）（上海 200025）；3 牛津大学人口健康纳菲尔德大数据研究所；4 中山大学中山医学院；5 布朗大学医学院国际健康研究中心；6 德国柏林自由大学与洪堡大学、夏里特医科大学全球卫生中心国际卫生研究所；7 瑞士热带病与公共卫生研究所；8 江西省寄生虫病防治研究所；9 杭州医学院（浙江省医学科学院）；10 安徽省疾病预防控制中心；11 江苏省血吸虫病防治研究所；12 湖北省疾病预防控制中心；13 中国疾病预防控制中心；14 湖北省血吸虫病专科医院；15 安徽省东至县血吸虫病专科医院
  • 出版日期:2025-12-25 发布日期:2026-01-20
  • 通讯作者: 师颖瑞 shiyingrui@hnca.org.cn；周晓农 zhouxn@nipd.chinacdc.cn
  • 作者简介:李博，男，硕士，主任医师。研究方向：公共卫生管理 李石柱，男，博士，研究员。研究方向：寄生虫病流行病学、分子流行病学、媒传热带病防控研究
  • 基金资助:
    湖南省卫生健康委员会卫生健康科研课题（20255023）

Expert consensus on the ultrasound diagnostic pathway for schistosomiasis japonica⁃induced hepatic fibrosis

LI Bo1△, LI Shizhu2△, XU Jing2, GUO Zhaoyu2, 3, WU Zhongdao4, WU Haiwei5, RICHTER Joachim6, 7, NING An8, WEN Liyong9, ZHANG Shiqing10, LIN Dandan8, YANG Kun11, HUA Haiyong11, SUN Xi4, YUAN Yi12, LI Huazhong13, YANG Miyang4, HE Dehui14, CAO Chengbin10, WU Bin15, ZHU Longqiang15, YAN Feixiong1, ZHENG Mao1, WANG Hongbo1, PAN Ge1,  TIAN Ying1, LI Jun1, LI Weixiang1, DUAN Juan1, GONG Chun1, REN Guanghui1, SHI Yingrui1*, ZHOU Xiaonong2*   

  1. 1 Hunan Institute of Schistosomiasis Control (The Third People's Hospital of Hunan Province), WHO Collaborating Centre on Schistosomiasis Control in Lake Regions, Regional Collaboration Centre for Schistosomiasis Control Technology in Lake Regions, Hunan Provincial Key Laboratory of Immunology and Transmission Control on Schistosomiasis, National Clinical Center for Schistosomiasis Treatment, Yueyang, Hunan 414000, China; 2 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai 200025, China; 3 Big Data Institute, Nuffield Department of Population Health, University of Oxford, the United Kingdom; 4 Zhongshan School of Medicine, Sun Yat⁃sen University, China; 5 Center for International Health Research, Warren Alpert School of Medicine, Brown University, the United States; 6 Institute of International Health, Charité Centre for Global Health, Charité University Medicine; Free University and Humboldt University of Berlin, Germany; 7 Swiss Tropical and Public Health Institute, Switzerland; 8 Jiangxi Provincial Institute of Parasitic Diseases, China; 9 Hangzhou Medical College (Zhejiang Academy of Medical Sciences), China; 10 Anhui Provincial Center for Disease Control and Prevention, China; 11 Jiangsu Institute of Parasitic Diseases, China; 12 Hubei Provincial Center for Disease Control and Prevention, China; 13 Chinese Center for Disease Control and Prevention, China; 14 Hubei Provincial Specialized Hospital for Schistosomiasis, China; 15 Dongzhi County Specialized Hospital for Schistosomiasis, Anhui Province, China
  • Online:2025-12-25 Published:2026-01-20

PDF

摘要： 超声检查因其无创、可重复等特点，能清晰显示血吸虫感染引起的肝纤维化及相关病变，是流行区血吸虫病筛查和疗效评估的重要手段。 随着我国血吸虫病防治工作的深入开展，新发感染已日趋减少，加强对既往感染者的管理、延缓肝纤维化进展，对实现消除目标至关重要。为此，中国疾病预防控制中心寄生虫病预防控制所于2025年5月组织来自国内多家血吸虫病防治、科研机构以及瑞士、美国的30余位专家，在回顾超声诊断标准化发展历程的基础上，研讨形成了日本血吸虫病肝纤维化超声诊断路径专家共识，旨在为超声技术应用于血吸虫病肝纤维化筛查及干预方案制定提供科学依据。

关键词: 日本血吸虫病, 肝纤维化, 超声, 诊断路径, 专家共识

Abstract: Due to non⁃invasive and repeatable characteristics, ultrasound, which may clearly display hepatic fibrosis and related pathologies caused by Schistosoma infections, is a vital tool for schistosomiasis screening and evaluation of therapeutic efficacy in endemic areas. With the progress towards elimination of schistosomiasis, there is an increasing reduction in new infections in China, and intensified management of previous infections and a delayed progress of hepatic fibrosis are therefore critical to the target of schistosomiasis elimination in the country. On May 2025, National Institute of Parasitic Diseases, Chinese Centre for Disease Control and Prevention convened an international seminar on ultrasound diagnosis of schistosomiasis japonica⁃induced hepatic fibrosis, which included over 30 experts from China, Switzerland and the United States, and achieved on expert consensus on the ultrasound diagnostic pathway for schistosomiasis japonica⁃induced hepatic fibrosis, based on a review of the historical development of standardization of ultrasound diagnosis, aiming to provide insights into the application of ultrasound technology in guiding the formulation of screening of schistosomiasis⁃induced hepatic fibrosis and interventions.  

Key words: Schistosomiasis japonica, Hepatic fibrosis, Ultrasound, Diagnostic pathway, Expert consensus

中图分类号: 

 苏公网安备32021102001651   苏ICP备11056399号-2
版权所有 © 江苏省血吸虫病防治研究所
地址：江苏省无锡市梅园杨巷117号　邮编：214064
电话：0510-68781021、68781022　 传真：0510-85510263　 Email：xfbjb@vip.163.com
技术支持：北京玛格泰克科技发展有限公司