Abstract: Objective To discuss the therapy for acute gastric mucosal lesion（AGML）after pericardial devascularization of advanced schistosomiasis. Methods Fifteen advanced schistosomiasis patients with AGML after pericardial devascularization re? ceived supporting therapy，reducing stomach acid and protecting gastric mucosa therapy，reducing gastric blood flow therapy，en? doscopic spraying topical hemostatic agents or electric coagulation therapy，etc. Results After pericardial devascularization of ad? vanced schistosomiasis，15 patients occurred AGML，and among which，10 cases occurred from 8 to 14 days，and the shortest pe? riod was 5 days and the longest was 23 days. Among the 15 patients，13 patients were cured（86.7%），and 2 died. Conclusion The comprehensive therapy including supporting therapy，reducing gastric acid and protecting gastric mucosa，and endoscopic he? mostasis is effective in the treatment of AGML.

Key words: Advanced schistosomiasis； Acute gastric mucosal lesion（AGML）； Pericardial devascularization

摘要： 目的 目的 探讨晚期血吸虫病患者贲门周围血管离断术后急性胃黏膜病变 （AGML） 的治疗方法。方法 方法 选择1991? 2010年湖北省潜江市血吸虫病预防控制所收治的晚期血吸虫病患者贲门周围血管离断术后AGML 15例。给予支持疗法、 降低胃酸和保护胃黏膜、 减少胃黏膜血流、 内镜下局部喷洒止血剂或电凝止血等方法治疗。结果 结果 15例贲门周围血管离 断术后发生AGML， 最短5 d， 最长23 d， 8～14 d 10例。13例治愈， 治愈率达86.67%， 2例死亡。结论 结论 支持疗法、 降低胃酸 和保护胃黏膜、 内镜下止血等综合疗法是治疗AGML的有效方法。

关键词: 晚期血吸虫病； 急性胃黏膜病变； 贲门周围血管离断术