Abstract:

Objective To understand the situation of Toxoplasma gondii infection among pregnant women in Jiangsu Prov?
ince. Methods The pregnant women from 7 cities in Jiangsu Province were involved in this survey and the information was record?
ed according to the request of unified admission information of the case questionnaire of toxoplasmosis in Jiangsu Province. The
specific antibodies IgM and IgG to Toxoplasma gondii in sera of these pregnant women were tested by ELISA. Results The specif?
ic antibody IgM to Toxoplasma gondii of all the respondents was negative. The positive rate of IgG was 3.98%（43/1 081），which
was little different from the control group’s 2.27%（4/176），and every city shared a similar positive rate. The positive rate of IgG
of early pregnant women was 3.78%，which was also not obviously different from the 4.17% appearing in mid and late pregnant
women. The respondents who previously had pathological abortions did not show positive IgG. Only 1.84%（8/435）of pregnant
women had had the examinations related to Toxoplasma gondii before this survey. Conclusions The rate of Toxoplasma gondii in?
fection is low among pregnant women in Jiangsu Province. The situations in different areas are not far from each other. We should
enhance the peri?conception tests of Toxoplasma gondii and take prevention and treatment countermeasures based on correspond?
ing objects，and also further strengthen the healthy education.

Key words: Toxoplasma gondii；Toxoplasmosis；Pregnant women；Jiangsu Province；

摘要：

目的 了解江苏省孕妇弓形虫感染情况。 方法 2009-2010年选择全省7个市的孕妇作为调查对象，采用酶联免疫吸附试验检测抗弓形虫特异性抗体IgM、IgG。按照《江苏省弓形虫病个案调查表》统一录取信息进行统计分析。结果1 081名孕妇弓形虫IgM均为阴性，IgG阳性率为3.98%（43/1 081），与对照组的2.27%（4/176）差异无统计学意义（ χ2 =1.23，P ＞ 0.05）；各市间阳性率差异无统计学意义（ χ2 = 2.07，P ＞ 0.05）。IgG阳性率早孕组为3.78%，中晚孕组为4.17%，与对照组3组间差异无统计学意义（ χ2 = 1.33，P ＞ 0.05）。既往有病理性流产史的孕妇无弓形虫IgG阳性者。仅1.84%（8/435）的孕妇曾做过弓形虫相关检测。结论 江苏省孕妇弓形虫感染率处于较低状态，地区间差异不大；应积极开展围孕期弓形虫检测，根据不同对象采取相应的防治对策；同时需进一步在居民中开展加强弓形虫病防治知识的健康教育。［关键词］ 弓形虫；弓形虫病；孕妇；江苏省