Chinese Journal of Schistosomiasis Control ›› 2024, Vol. 36 ›› Issue (2): 184-190.

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Bibliometric analysis of researches on the Plasmodium falciparum repetitive interspersed families of polypeptides protein from 1993 to 2022

YIN Jingxian1, SUN Zhishan1, ZHAO Hanqing1, ZHOU Xiaonong1, 2, 3, Kassegne Kokouvi1, CHEN Junhu1, 2, 3*   

  1. 1 School of Global Health, Shanghai Jiao Tong University School of Medicine and Chinese Center for Tropical Diseases Research,Institute of One Health, Shanghai Jiao Tong University, Shanghai 200025, China; 2 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), National Health Commission Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai 200025, China; 3 Hainan Tropical Diseases Research Center (Hainan Sub⁃center, Chinese Center for Tropical Diseases Research), Haikou, Hainan 571199, China
  • Online:2024-04-15 Published:2024-05-24

1993—2022年恶性疟原虫RIFIN蛋白研究文献计量学分析

尹静娴1,孙芷珊1,赵翰卿1,周晓农1,2,3,Kassegne Kokouvi1,陈军虎1,2,3*   

  1. 1 上海交通大学医学院⁃国家热带病研究中心全球健康学院、上海交通大学全健康研究中心(上海 200025);2 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心)、国家卫生健康委员会寄生虫病原与媒介生物学重点实验室、WHO热带病合作中心、科技部国家级热带病国际联合研究中心(上海 200025);3 海南热带病研究中心(国家热带病研究中心海南分中心)(海南 海口 571199)
  • 作者简介:尹静娴,女,硕士研究生。研究方向:寄生虫病防治、公共卫生、全健康
  • 基金资助:
    国家重点研发计划(2018YFE0121600)

Abstract: Objective To perform a bibliometric analysis of researches on the Plasmodium falciparum repetitive interspersed families of polypeptides (RIFIN) protein from 1993 to 2022 and identify the hot topics in the RIFIN protein research, so as to provide insights into future researches on RIFIN protein. Methods RIFIN protein⁃associated publications were retrieved in the Web of Science Core Collection from 1993 to 2022 and all bibliometric analyses were performed using the software CiteSpace 6.2.4.0. The annual number of RIFIN protein⁃associated publications was analyzed from 1993 to 2022, and country, author and institution collaboration networks were created. Keywords were extracted from RIFIN protein⁃associated publications for plotting keyword co⁃occurrence, clustering, burst and timeline maps to identify the hot topics in the RIFIN protein research. Results A total of 745 English RIFIN protein⁃associated publications were included in the final bibliometric analysis, and there 18 to 36 publications each year from 1993 to 2022. The top three countries with the highest activity in the RIFIN protein research included the United States, the United Kingdom and France, universities and research institutes were highly active in the RIFIN protein research; however, no authors were identified with a high activity in the RIFIN protein research. There were three keyword clusters in the RIFIN protein⁃associated publications, including repetitive DNA sequence, molecular epidemiology and antigenic variation. Keyword co⁃occurrence, burst and timeline analyses showed that previous RIFIN protein⁃associated publications mainly focused on gene properties and functions, involving keywords of repetitive DNA sequence and evolution, and recent hot topics for the RIFIN protein research shifted to genetic diversity and immune response, involving keywords of genetic diversity, antigenic variation and binding. Conclusions The annual number of RIFIN protein⁃associated publications was relatively stable from 1993 to 2022. This bibliometric analysis may provide insights into future researches on the RIFIN protein.

Key words: Plasmodium falciparum, Repetitive interspersed families of polypeptides, Bibliometric analysis, CiteSpace

摘要: 目的 对1993—2022年恶性疟原虫重复散布蛋白家族(repetitive interspersed families of polypeptides,RIFIN)研究文献进行文献计量学分析,总结研究热点,为RIFIN蛋白后续研究提供参考。方法 在Web of Science核心合集数据库中检索1993—2022年RIFIN蛋白研究相关论文,采用CiteSpace 6.2.4.0软件分析1993—2022年各年发文量并构建国家、作者、机构合作网络图谱;提取文献的关键词绘制关键词共现、聚类、突现和时间线图谱,分析RIFIN蛋白研究热点。结果 共纳入745篇英文文献进行文献计量学分析,1993—2022年年发文量为18~36篇。RIFIN蛋白研究领域活跃度居前3位的国家为美国、英国、法国,活跃度较高的机构是高校和研究机构,未发现活跃度特别高的作者。关键词共形成重复DNA序列、分子流行病学、抗原变异等3个聚类。关键词共现、突现和时间线分析结果显示,既往RIFIN蛋白研究主要集中在基因性质、功能等方面,涉及的关键词包括重复DNA序列、进化等;近年来研究热点转向基因多样性和免疫反应等方面,涉及的关键词包括基因多样性、抗原变异、结合等。结论 1993—2022年RIFIN蛋白研究相关论文逐年发文量相对稳定,本研究结果可望为RIFIN蛋白后续研究提供借鉴。  

关键词: 恶性疟原虫, 重复散布蛋白家族, 文献计量学分析, CiteSpace

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