Chin J Schisto Control ›› 2018, Vol. 30 ›› Issue (3): 289-294.

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Epidemic situation of imported malaria and diagnostic capabilities of medical institutions in Wuhan City from 2008 to 2017

WU Kai| CHEN Fang| XU Ming-xing| YANG Yan*   

  1. Wuhan Center for Disease Prevention and Control| Hubei Province| Wuhan 430015| China
  • Online:2018-07-02 Published:2018-07-02
  • Contact: YANG Yan

2008-2017年武汉市境外输入性疟疾疫情及诊断能力分析

吴凯|陈芳|徐明星|杨燕*   

  1. 湖北省武汉市疾病预防控制中心(武汉 430015)
  • 通讯作者: 杨燕
  • 作者简介:吴凯|男|硕士|副主任技师。研究方向:寄生虫病防治
  • 基金资助:
    湖北省武汉中青年医学骨干人才培养工程;湖北省武汉市2015年度医疗卫生科研项目(WG15C05)

Abstract: Objective To understand the epidemiological characteristics of imported malaria and the control and diagnostic capacities of the medical institutions in Wuhan City, so as to offer the evidence for formulating the surveillance and control strategies. Methods From 2008 to 2017, the epidemiological data of imported malaria were collected. The information including gender, age, distribution, vocational background, positive rate of fever patients, and time of final diagnosis was analyzed with the descriptive statistic method. The Plasmodium species composition and infection source were analyzed by chi square test. The initial and confirmed diagnosis abilities of medical institutions were analyzed by rank sum test. Results Totally, 424 imported malaria cases were reported, including 301 falciparum malaria cases (70.99%). The male population aged 20 to 49 years was the main morbidity group, and the incidence was not related to seasons. For the parasite species, there was a significant difference between African countries and Southeast Asian countries ([χ2] = 205.83,[P<0.01]). Plasmodium ovale and P. malariae were all imported from sub?Saharan Africa. For diagnostic capacities of the medical institutions at different levels, the initial diagnosis (Z = -3.89,P < 0.01) and confirmed diagnosis ([χ2] = 53.88,[P<0.01]) were significantly different, respectively. The ability of malaria diagnosis was improved rapidly in the clinical laboratory after 2008 and achieved to 100% in 2010. The detection rate within 24 hours increased to at least 90% and the detection rate within 6 days decreased to 0 in 2016. Conclusions Although the medical institutions in Wuhan City have strong ability to treat imported malaria, they are still faced with a serious situation for malaria control and elimination. The capacity building should be strengthened constantly.

Key words: Imported malaria; Epidemic situation; Diagnostic capability; Wuhan City

摘要: 目的 分析湖北省武汉市境外输入性疟疾流行特征、医疗机构防治和诊断能力,为输入性疟疾监测和制定防控策略提供科学依据。方法 收集2008-2017年武汉市境外输入性疟疾病例流行病学资料,对病例性别、年龄、地区、职业、发病时间、血检阳性率、入院?检出时间采用描述性分析,对虫种、疫源地、就诊情况进行统计分析。结果 2008-2017年武汉市共报告境外输入性疟疾424例,其中恶性疟301例(70.99%),20 ~ 49岁男性为主要发病群体,发病无季节相关性。非洲和东南亚地区输入性病例的疟原虫感染类型不同([χ2] = 205.83,P < 0.01),卵形疟和三日疟均来自非洲撒哈拉沙漠以南国家。不同级别医疗机构初诊(Z = -3.89,P < 0.01)和确诊([χ2] = 53.88,P < 0.01)能力差异有统计学意义。2008年后医院发热门诊血检能力快速提升,至2010年实现所有疟疾病例均在实验室(镜检)诊断,且24 h检出率逐年提高至90%以上,而6 d检出率降至0(2016年)。结论 虽然武汉市医疗机构应对境外输入性疟疾能力已处于较高水平,但输入性疟疾防控形势依然较严重,须持续加强医疗机构的相关能力建设。

关键词: 输入性疟疾;疫情;诊断能力;武汉市

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