Chin J Schisto Control ›› 2020, Vol. 32 ›› Issue (2): 187-.

Previous Articles     Next Articles

Acute toxicity of four heavy metal ions to Oncomelania hupensis

ZHANG Qin1, GAO Meng-Yang1, ZHOU Shu-Lin1*, ZENG Xiao-Long2   

  1. 1 Department of Medical Parasitology, School of Basic Medical Sciences, Wannan Medical College, Wuhu 241002, China; 2 School of Clinical Medicine, Wannan Medical College, China
  • Online:2020-04-30 Published:2020-04-30

4种重金属离子对湖北钉螺的急性毒性作用

章琴1,高梦阳1,周书林1*,曾晓龙2   

  1. 1皖南医学院基础医学院医学寄生虫学教研室(芜湖241002);2皖南医学院临床医学院
  • 作者简介:章琴,女,硕士研究生。研究方向:血吸虫病控制
  • 基金资助:
    安徽省自然科学基金(11040606M214)

Abstract: Objective To assess the acute toxicity of Cu2+, Cd2+, Hg2+ and Pb2+ to Oncomelania hupensis. Methods Cu2+, Cd2+, Hg2+ and Pb2+ solutions were prepared at five concentrations, and 10 snails were exposed to each concentration for 24, 48, 72 h and 96 h. Then, the inhibition of snail activity and snail death was observed, and the half maximal effective concentration (EC50) and median lethal concentrations (LC50) were estimated. Results The 24, 48, 72 h and 96 h EC50 values of Cu2+, Cd2+, Hg2+ and Pb2+ were 0.74, 0.56, 0.46, 0.37 mg/L, 4.79, 3.52, 1.70, 1.26 mg/L, 1.90, 1.49, 0.83, 0.76 mg/L and 21.40, 9.98, 7.90, 5.42 mg/L for snails, respectively. The 96 h LC50 values of Cu2+, Cd2+, Hg2+ and Pb2+ were 0.43, 2.96, 1.12 mg/L and 12.22 mg/L for snails, the safe concentrations were 0.004 3, 0.029 6, 0.011 2, 0.122 2 mg/L, respectively. Conclusion Cu2+ shows a high acute toxicity to snails, and Cd2+ and Hg2+ exhibit a moderate acute toxicity to snails, while Pb2+ is lowly toxic to snails.

Key words: Oncomelania hupensis, Cu2+, Cd2+, Hg2+, Pb2+, Acute toxicity

摘要: 目的 评价Cu2+、Cd2+、Hg2+、 Pb2+对湖北钉螺的急性毒性作用。方法 分别配置5个浓度Cu2+、Cd2+、Hg2+、Pb2+溶液,每组投放10只钉螺,观察24、48、72、96 h后钉螺活动受抑制情况,计算半数有效浓度(EC50);统计96 h时钉螺死亡数量,计算半数致死浓度(LC50)和安全浓度。结果 Cu2+对钉螺24、48、72、96 h EC50值分别为0.74、0.56、0.46、0.37 mg/L,Cd2+分别为4.79、3.52、1.70、1.26 mg/L,Hg2+分别为1.90、1.49、0.83、0.76 mg/L,Pb2+分别为21.40、9.98、7.90、5.42 mg/L。Cu2+、Cd2+、Hg2+、Pb2+对钉螺96 h LC50值分别为0.43、2.96、1.12、12.22 mg/L,安全浓度分别为0.004 3、0.029 6、0.011 2, 0.122 2 mg/L。结论 Cu2+对钉螺的急性毒性为高毒,Cd2+和Hg2+为中毒,Pb2+为低毒。

关键词: 湖北钉螺, Cu2+, Cd2+, Hg2+, Pb2+, 急性毒性

CLC Number: