Chin J Schisto Control ›› 2019, Vol. 31 ›› Issue (4): 439-.

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Epidemiological investigation of blood transfusion?-nduced malaria caused by an imported case with Plasmodium falciparum infection

HUANG Wen-Ming*, CHEN Jian-Feng, ZHANG Xiang, HE Yi-Lin   

  1. Taizhou Municipal Center for Disease Control and Prevention, Jiangsu Province, Taizhou 225300, China
  • Online:2019-09-27 Published:2019-09-27

1例由输入性疟疾感染者引起输血疟疾的调查

黄文明*,陈剑峰,张翔,何义林   

  1. 江苏省泰州市疾病预防控制中心(泰州 225300)
  • 作者简介:黄文明,男,本科,副主任医师。研究方向:寄生虫病预防与控制

Abstract: Objective To analyze a case infected with Plasmodium falciparum due to blood transfusion in Taizhou City, so as to provide scientific evidence for malaria control. Methods The epidemiological investigation of a case with P. falciparum malaria was conducted, and the blood donors’ blood samples were collected and detected in laboratory to identify the origin of the infection. Results Microscopy detected Plasmodium in the blood samples from a 64?year?old male inpatient with nephropathy, and P. falciparum malaria was diagnosed. The case had no history of travel to Africa or Southeast Asia except blood transfusion, and he had received blood transfusion 14 times during his hospital stay. Detection of blood donors’ blood samples showed P. falciparum in the archived blood samples from an Indonesian student studying in China, as revealed by PCR assay, and the student was found to have a history of malaria. Conclusions The patient was confirmed to be a case with P. falciparum malaria due to blood transfusion. Screening of malaria should be intensified in blood donors to prevent the development of malaria transmitted by blood transfusion.

Key words: Falciparum malaria, Blood transfusion, Epidemiological investigation, Taizhou City

摘要: 目的 对泰州市1例因输血感染恶性疟的病例进行分析,为疟疾防控提供科学依据。方法 对1例恶性疟患者开展流行病学追踪调查,通过实验室方法对供血者血样进行检测,以明确感染来源。结果 1名64岁肾病住院患者的血液标本镜检查见疟原虫,确诊为恶性疟。经流行病学调查,患者除接受过输血外,无非洲和东南亚等恶性疟流行区旅行史;住院期间曾接受14次输血治疗,对23份供血者血样进行检测,发现1名印度尼西亚籍留学生留存血样PCR检测呈恶性疟原虫阳性,流行病学调查发现该供血者曾有疟疾感染史。结论 该患者为输血感染恶性疟病例,应加强对献血者的疟疾筛查,以预防输血传播疟疾的发生。

关键词: 恶性疟, 输血, 流行病学调查, 泰州市

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