Chin J Schisto Control ›› 2018, Vol. 30 ›› Issue (5): 555-558.

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Epidemic situation and diagnosis and treatment of severe falciparum malaria in Nantong City

CAO Cai-qun1| DING Gui-sheng1| WANG Wei-ming2*   

  1. 1 Nantong Center for Disease Control and Prevention| Jiangsu Province| Nantong 226007| China;2 Jiangsu Institute of Parasitic Diseases| China
  • Online:2018-12-01 Published:2018-12-01
  • Contact: WANG Wei?ming



  1. 1 江苏省南通市疾病预防控制中心(南通226007);2 江苏省寄生虫病防治研究所
  • 通讯作者: 王伟明
  • 作者简介:曹彩群|女|本科|副主任医师。研究方向:寄生虫病控制
  • 基金资助:

Abstract: Objective To retrospectively analyze the epidemic situation and diagnosis and treatment of severe falciparum malaria in Nantong City, summarize the causes of severe falciparum malaria, and evaluate the effect of diagnosis and treatment, so as to provide the evidence for formulating the practical treatment measures for this disease. Methods All the data of falciparum malaria cases in Nantong City from 2009 to 2016 were collected and analyzed for the onset time, diagnosis process and treatment of the disease. Results A total of 359 malaria cases, including 289 falciparum malaria cases, were reported in Nantong City from 2009 to 2016, including 26 severe falciparum malaria cases. All the severe falciparum malaria cases were imported from Africa, including 57.70% of cases (15/26) from Angola. All of them were male labor exporting personnel. The incidence of malaria was not obviously seasonal. The average time from onset to definite diagnosis was 5.2 days, and 11 cases were diagnosed 5 days after the onset. All the 26 cases were cured by anti?malaria treatment and symptomatic treatment, and there was no death. Conclusions Severe falciparum malaria seriously harm the people’s health and its clinical manifestations are complicated. Therefore, the training of medical staff and health education in residents, especially in labor exporting personnel, should be further strengthened.

Key words: Falciparum malaria; Imported case; Severe malaria; Nantong City

摘要: 目的 回顾性分析南通市重症疟疾病例特征和诊治情况,总结重症疟疾的成因、评价诊治效果,为制定切实可行的重症疟疾救治措施提供科学依据。方法 收集2009-2016年南通市所有疟疾病例资料,对重症疟疾病例的发病时间、临床表现、诊断过程、治疗情况进行汇总分析。结果 2009-2016年南通市共报告疟疾病例359例,其中重症病例26例,均为境外输入性恶性疟病例,其中脑型疟12例、急性肾功能衰竭11例、重度贫血3例。26例重症疟疾病例从发病至就诊的平均时间为3.1 d,平均时间最长者在发病第12天才就诊;从发病至确诊的平均时间为5.2 d,其中11例在发病5 d后得到确诊。乡(镇)医院首诊确诊率为25.00%(1/4),县级医疗机构首诊确诊率为90.91%(10/11)。26例重症疟疾病例通过抗疟治疗和临床对症治疗均治愈,无死亡病例。结论 重症疟疾临床表现复杂、并发症多、危害严重,加大对赴疟疾高度流行区人员的疟疾宣教、提高诊治单位医务人员对疟疾的诊治能力和镜检技能,可有效减少重症恶性疟病例发生、避免疟疾病例死亡。

关键词: 恶性疟;输入性病例;重症疟疾;南通市

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