Chin J Schisto Control ›› 2018, Vol. 30 ›› Issue (2): 219-221.

### Prevalence of Clonorchis sinensis infection and effect of albendazole treatment among residents in two communities of Zhongshan City

ZHENG Ying-yan1*| XIE Ting-jun1| WANG Man2| FANG Yue-yi3| LUO Le2

1. 1 Zhongshan Torch High?tech Industrial Development Zone of Community Health Service Center| Guangdong Province| Zhongshan 528400| China； 2 Zhongshan Municipal Center for Disease Control and Prevention| Guangdong Province| China； 3 Guangdong Provincial Center for Disease Control and Prevention| China
• Online:2018-05-11 Published:2018-05-14

### 中山市2个社区居民华支睾吸虫感染情况及阿苯达唑疗效分析

1. 1 广东省中山市火炬高技术产业开发区社区卫生服务中心（中山 528400）；2 广东省中山市疾病预防控制中心；3 广东省疾病预防控制中心
• 作者简介:郑迎燕|女|本科|主管医师。研究方向：疾病控制

Abstract: Objective To understand the prevalence of Clonorchis sinensis infection among residents in two communities of Zhongshan City， and evaluate the effect of albendazole treatment， so as to offer the evidence for formulating the strategy of clonorchiasis prevention and control. Methods The stool specimens were collected from the residents of two comprehensive demonstration areas， and the eggs of C. sinensis were detected by Kato?Katz technique. Those who were tested positive were treated with albendazole （0.4， twice a day for 4 days in adults， and half dosage for children aged 16 years or below）. Three weeks after the treatment， the stool specimens were recollected and retested to evaluate the effect. Results A total of 532 people were investigated and 96 were tested positive， with an infection rate of 18.05%. The infection rate was 28.63% （69/241） in the males and 9.28% （27/291） in the females， and there was a significant difference between them （[χ2] = 334.99， [P<0.01]）. The infection rate increased with the increase of the age （[χ2] = 63.84，[ P<0.01]）. Among the 96 positive residents， 94 received the albendazole treatment， and 86 were retested after the treatment with a negative conversion rate of 91.86% （79/86）. Of the 7 residents without the conversion， 5 had irregular medication. No severe adverse reactions were reported during the period of treatment. Conclusions The infection rate of C. sinensis among residents in the two communities of Zhongshan City is high， especially among the males and aged people. The effect of albendazole is good in the treatment of C. sinensis infection. In the future， the general survey and treatment should be strengthened in order to lower the infection rate.

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