Abstract: Objective To understand the prevalence of Toxoplasma gondii infection and its risk factors among healthy blood donation population in Shijiazhuang City， Hebei Province， so as to provide the evidence for developing effective prevention and control measures. Methods A total of 1 630 cases of blood donors in Shijiazhuang City were chosen as respondents， and all the respondents were qualified to the standard of blood donation. The antibodies to T. gondii were detected by using ELISA. The infection rates of T. gondii in blood donation population were compared between/among different genders， ages， occupations， education levels， and places of residence. The risk factors for Toxoplasma infection were surveyed with questionnaires. Results A total of 1 630 cases of healthy blood donors were investigated， and among which 126 cases were positive in the detection of antibodies to T. gondii and the positive rate was 7.73%. The positive rates between/among the different genders， ages， occupations， and education levels were significantly different （[χ2]＝4.36， 13.98， 9.71， 7.65， respectively， all P < 0.05）， and the positive rates among different places of residence were not significantly different （[χ2]＝1.63， P＞0.05）. The questionnaire survey showed that the T. gondii infection was closely related to keeping pets， outside eating frequently， having chafing dish or barbecue， sharing cutting board for cooked and uncooked food， and no the habit of washing hands before meals. Conclusions The infection rate of T. gondii is relatively high among the healthy blood donation population in Shijiazhuang region. The cognitive education for T. gondii infection and infection monitoring are the keys to avoid the transfusion infection.

Key words: Toxoplasma gondii； Blood donation population； Infection； Risk factor

摘要： 目的 调查了解河北省石家庄地区健康献血人群弓形虫感染现状及危险因素，为制定科学有效的防治措施提供依据。方法 选择石家庄市1 630例符合献血者健康检查标准的无偿献血者为调查对象，采用酶联免疫吸附法（ELISA）检测弓形虫抗体。对比分析不同性别、年龄、职业、文化程度、居住地献血人群的弓形虫感染率。对弓形虫感染危险因素进行问卷调查，对调查结果进行统计分析。结果 在1 630例健康献血者中，共检出弓形虫抗体阳性126例，感染率为7.73%。不同性别、年龄、职业、文化程度献血人群弓形虫感染率比较，差异均有统计学意义（[χ2]＝ 4.36、13.98、9.71、7.65，P均< 0.05）；不同居住地献血人群弓形虫感染率无明显差异（[χ2]＝ 1.63，P > 0.05）。问卷调查结果显示，弓形虫感染与饲养宠物、经常在外就餐、喜吃火锅或烧烤、生熟食共用砧板、无饭前洗手习惯等不良生活卫生习惯密切相关（[χ2]＝35.90、175.44、7.41、15.72、6.94，P均< 0.01）。结论 河北石家庄地区健康献血人群有一定的弓形虫感染率。加强献血者弓形虫认知教育和感染监测是避免输血感染的重要环节。

关键词: 弓形虫；献血人群；感染；危险因素