Chin J Schisto Control ›› 2016, Vol. 28 ›› Issue (2): 128-134,155.

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Investigation on prevalence and risk factors of HIV/AIDS and Schistosoma japonicum, Ascaris lumbricoides and Trichuris trichiura infections in a rural community of southwestern

XIAO Peng-lei,ZHOU Yi-biao* ,SHI Yan,YANG Yan, GAO Jian-chuan,SONG Xiu-xia, JIANG Qing-wu   

  1. Department of Epidemiology,School of Public Health,Fudan University;Key Laboratory of Public Health Safety,Ministry of Ed? ucation; Fudan University Center for Tropical Disease Research,Shanghai 200032, China
  • Online:2016-04-19 Published:2016-04-20
  • Contact: ZHOU Yi?biao

我国西南彝族农村地区HIV与血吸虫 蛔虫及鞭虫感染现状调查


  1. 复旦大学公共卫生学院流行病学教研室、 公共卫生安全教育部重点实验室、 复旦大学热带病研究中心 (上海 200032)
  • 通讯作者: 周艺彪
  • 作者简介:肖鹏磊, 女, 硕士研究生。研究方向: HIV及血吸虫感染对人体免疫功能的影响

Abstract: Objective Objective To investigate the prevalence and risk factors of helminthic infections including Schistosoma japoni? cum,Ascaris lumbricoides and Trichuris trichiura and human immunodeficiency virus(HIV),and find out the association among them in a rural community of southwestern China. Methods Methods A community?based cross sectional study was conducted. One town was selected randomly;the infections of S. japonicum,A. lumbricoides and T. trichiura were detected with the modi? fied Kato?Katz thick smear method and HIV infection with the diagnostic Test Kit among all residents. A questionnaire survey was conducted to investigate the related risk factors. Results Results Among the participants,the infection rates of HIV,S. japoni? cum,A. lumbricoides and T. trichiura were 2.33%,2.05%,13.47% and 30.59% respectively;7.08%(31/438)were infected with both A. lumbricoides and T. trichiura;0.23%(1/438)were co?infected with HIV and A. lumbricoides,and the same with HIV and T. trichiura. The multivariate logistic regression analysis showed that sex(male,OR=3.26,95% CI: 0.97,10.95)and drug abuse(OR=72.86,95% CI: 18.51,286.76)were significantly associated with HIV infection. Home toilet was negatively related to A. lumbricoides infection(OR=0.52,95% CI: 0.27,0.98)and T. trichiura infection(OR=0.48,95% CI: 0.28, 0.80) . Compared with the people in Villages Four,the people living in Village One were at a higher risk for A. lumbricoides in? fection(OR=3.14,95% CI: 1.35,7.27),and compared with the people living in Village Four,the people living in Village Two and Village Three were more likely to be infected with T. trichiura(OR=3.73,95% CI: 1.92,7.26;OR=4.53,95% CI:2.12, 9.68) . The people aged between 11 and 20 years had a higher T. trichiura infection risk than the people aged more than 50 years (OR = 3.72,95% CI: 1.59,8.67) . There was a significant association between A. lumbricoides and T. trichiura infections (OR = 3.11,95% CI:1.63,5.93) . There was no association between S. japonicum infection and related factors above men? tioned. Conclusions Conclusions The infection rates of HIV,S. japonicum,A. lumbricoides and especially T. trichiura were rather high in this area,and therefore,the prevention and treatment of these diseases should be strengthened. Further studies on the relation? ship between HIV and the infections of helminths, especially S. japonicum are needed.

Key words: Schistosomiasis, Human immunodeficiency virus(HIV), Ascaris lumbricoides, Trichuris trichiura, Cross? sectional study, Rural area, Yi nationality

摘要: 目的 目的 了解我国西南彝族农村地区HIV、 血吸虫、 蛔虫及鞭虫感染状况, 调查是否存在混合感染。 方法 方法 在我 国西南部某山区随机选取一个彝族乡开展横断面调查, 检测村民HIV、 血吸虫、 蛔虫及鞭虫感染情况; 并对村民进行问卷 调查, 了解HIV及寄生虫感染的危险因素。 结果 结果 我国西南彝族农村地区居民HIV、 血吸虫、 蛔虫和鞭虫感染率分别为 2.33%、 2.05%、 13.47%和30.59%, 鞭虫与蛔虫共同感染检出率为7.08%, HIV与蛔虫和鞭虫共同感染检出率均为0.23%。 男性以及吸毒是HIV感染的危险因素 [OR = 3.26, 95% CI:(0.97, 10.95); OR = 72.86, 95% CI: (18.51, 286.76)]; 厕所与蛔 虫和鞭虫感染间均存在负相关关系 [OR = 0.51, 95% CI:(0.27, 0.98); OR = 0.48, 95% CI:(0.28, 0.80)]。与居住在村4的 居民相比, 村1村民感染蛔虫风险较高 [OR = 3.14, 95% CI:(1.35, 7.27)]; 与居住在村4的居民相比, 居住在村2和村3的 村民鞭虫感染风险较高 [OR = 3.73,95% CI:(1.92, 7.26); OR = 4.53, 95% CI:(2.12, 9.68)]。此外, 11~20岁年龄组村民 鞭虫感染风险高于>50岁村民 [OR = 3.72, 95% CI:(1.59, 8.67)]; 蛔虫与鞭虫感染间存在相关关系 [OR = 3.11, 95% CI: (1.63, 5.93)], 未发现与血吸虫感染相关的因素。 结论 结论 我国西南彝族农村居民HIV及寄生虫感染率尤其是鞭虫感染 率较高; 应进一步探索HIV与寄生虫感染, 尤其是与血吸虫感染间的关系。

关键词: 血吸虫病, 人类免疫缺陷病毒, 蛔虫病, 鞭虫病, 横断面调查, 农村地区, 彝族

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