Abstract:

The specific molecular targets of schistosomula have been investigated for being new vaccine candidates. The mech? anism of the growth and development of the skin?stage，lung?stage and hepatic schistosomula may be related to the immune regula? tion，signal transduction，sex?differentiation and apoptosis. Actin et al are important molecules which related to the growth and de? velopment of schistosomula.

Key words: Schistosoma；Schistosomulum；Growth and development；Immune regulation；Important molecules

摘要：

血吸虫童虫是宿主免疫系统攻击的重要靶标，包括皮肤型、肺型和肝门型童虫。宿主分子对童虫生长发育具有重要作用。童虫生长发育机制包括免疫调节、信号转导、性别发育及凋亡等。肌动蛋白、组织蛋白酶、烯醇化酶和葡萄糖基转移酶等分子为血吸虫童虫生长发育的重要分子。本文对血吸虫童虫生长发育及其机制的研究进展做一综述。

关键词: 血吸虫；血吸虫童虫；生长发育；免疫调节；重要分子