Chin J Schisto Control ›› 2010, Vol. 22 ›› Issue (1): 31-34.

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Ultrasonographical characters and their changes due to Schistosoma japonicum infection in Poyang Lake region, Jiangxi Province

Liu Yue-min1, Lin Dan-dan1, Hu Fei1, Tao  Bo2, Jiang Qiu-lin2, Wang Jin-ming2, Li Jian-ying1   

  1. 1 Jiangxi Provincial Institute of Parasitic Diseases (Nanchang 330046)|2 Xingzi Station of Schistosomiasis Control, Jiangxi Province, China
  • Online:2010-02-15 Published:2010-03-10

鄱阳湖区血吸虫病疫区居民肝脾超声图像特征及转归评估

刘跃民1|林丹丹1|胡飞1|陶波2|姜秋林2|王金明2|李剑瑛1   

  1.  1 江西省寄生虫病防治研究所(南昌330046);2 |江西省星子县血吸虫病防治站
  • 通讯作者: 林丹丹
  • 作者简介:刘跃民|男|本科|副主任医师。研究方向:血吸虫病控制
  • 基金资助:

    江西省科技支撑项目(2007BS22501)

Abstract:

Objective To observe ultrasonographical characters and their changes in endemic areas of schistosomiasis japonica in Poyang Lake region, Jiangxi Province and to explore the value of ultrasound for assessment of the morbidity of the disease. Methods All permanent residents aged above 3 years old were examined by ultrasound and Kato-Katz method. Results The schistosome positive rates of fecalexaminations decreased greatly from 16.29% in 1995 to 8.54% in 2007(P value was less than 0.01). However, the rates of hepatomegaly and splenomegaly between 1995 and 2007 were not significantly changed(All P values were above 0.05), with the rates of 8.82% and 20.33% in 1995 and 8.54% and 21.34% in 2007, respectively. The abnormal rate of portal vein diameter decreased significantly, from 32.47% in 1995 to 6.50% in 2007. The abnormal rate of liver parenchyma increased remarkably( all P values were less than 0.01), from 34.85% to 51.83%. The changes of liver parenchyma Grade I showed a bidirectional trend, 29.90% of them changed into Grade 0 (normal image on ultrasonography), and 34.02% changed into Grade 2 and above. The abnormality of various indexes of ultrasonography examinations were related to age, occupation and schistosome infection status. Conclusion Ultrasonography can show the damages of liver and spleen in patients infected with Schistosoma japonicum directly, but it is necessary to study on further the sensitive indexes that reflecting early pathological changes and the best combination of the indexes for the assessment of schistosomiasis-related morbidity.

Key words: Schistosomiasis japonica, Ultrasonography, Poyang Lake region

摘要:

目的 观察鄱阳湖区血吸虫病疫区居民肝、脾超声图像特征及其转归,探讨超声显像(B超)在评估血吸虫病病情及其变化中的应用价值。方法 1995和2007年先后在江西省鄱阳湖区血吸虫病一重疫区村对常住居民同时采用病原学方法和B超进行检查。结果  1995与2007年居民粪检阳性率分别为16.29%和8.54%,差异有统计学意义(P<0.01);居民肝、脾肿大率分别为8.82%和20.33%、8.54%和21.34%,差异无统计学意义(P均>0.05);门静脉内径异常率分别为32.47%和6.50%,肝实质异常率分别为34.85%和51.83%,差异均有统计学意义(P均<0.01)。居民肝实质I级的发展具有双向性, 2007年检查结果表明,1995年肝实质Ⅰ级者中有29.90%恢复正常,34.02%发展为Ⅱ级以上。B超各项指标的改变与居民职业、血吸虫感染与否有关。结论  B超可用于诊断疫区居民血吸虫病病情和病理损伤,但其反映早期病变的敏感指标或评估病情状况的综合指标还有待进一步研究。

关键词: 日本血吸虫病, 超声显像, 鄱阳湖区