Abstract: Objective Objective To grasp the distribution and epidemiology of confirmed cases of schistosomiasis in Hubei Province， so as to provide the evidence for promoting the prevention and control work. Methods Methods The confirmed cases of schistosomiasis in Hubei Province from 2010 to 2014 were epidemiologically investigated，and the prevalence characteristics and main influenc? ing factors were analyzed. Results Results A total of 10 102 confirmed cases from 2010 to 2014 were surveyed. There were 1 062 local infected patients，accounting for 10.51% and including 354 repeated infections and 17 newly infected. There were 290 foreign? infected patients，accounting for 2.87%，with 206 repeated infection cases and 84 newly infected. There were 8 750 historical patients，including 2 229 patients who leaked the former schistosomiasis investigations，accounting for 22.06%；570 patients missed treatment，accounting for 5.64%；3 640 patients were treated with non?standard therapy，accounting for 36.03%；2 311 patients were treated with poor medication efficacy，accounting for 22.88%. The multivariate non?conditional Logistic regres? sion，targeting at confirmed cases in 2014，showed that，for the leaking investigations，the potential risk factors included the age，educational level，and latrine renovation（b＞0，OR＞1），the protective factors were the times of previous treatment，cat? tle feeding in villager team，and Oncomelania hupensis snails in surroundings（b＜0，OR＜1）；for the treatment?missing，the age，educational level，snails in the surroundings of residence were risk factors（b＜0，OR＜1）；for the substandard treat? ment，the risk factors included the occupation and snails in the surroundings of residence（b＞0，OR＞1），and the educational level and snails in the own field were protective factors（b＜0，OR＜1） . Conclusion Conclusion The epidemiological investigation on the confirmed cases of schistosomiasis could grasp the epidemic factors so as to improve the management and carry out the scientific control.

Key words: Schistosomiasis；Confirmed case；Epidemiological survey；Hubei Province

摘要： 目的 目的 了解湖北省血吸虫病确诊病例分布情况及流行特点， 为推进防治工作提供科学依据和技术保障。方 方 法 法 对2010-2014年湖北省血吸虫病确诊病例进行回顾性流行病学调查， 分析其流行特点和主要影响因素。结果 结果 2010-2014年湖北省共调查血吸虫病确诊病例10 102例。当年本地感染病人1 062例， 占10.51%， 其中重复感染354例， 新感染17例； 当年外地感染病人290例， 占2.87%， 其中重复感染206例， 新感染84例； 历史遗留病人8 750例， 其中漏查 病人2 229例， 占22.06%， 漏治病人570例， 占5.64%， 治疗不规范未愈病人3 640例， 占36.03%， 药物疗效不佳未愈病人 2 311例， 占22.88%。以2014年确诊病例为对象进行多因素Logistic回归分析， 结果表明， 对于漏查， 年龄、 文化程度、 卫 生改厕为危险因素 （b > 0， OR > 1）， 既往治疗次数、 本组饲养耕牛及居住地周围钉螺为保护因素 （b < 0， OR < 1）； 对于漏 治， 年龄、 文化程度、 居住地周围钉螺为危险因素 （b > 0， OR > 1）； 对于治疗不规范， 职业、 居住地周围钉螺为危险因素 （b > 0， OR > 1）， 文化程度、 自家地周围钉螺为保护因素 （b < 0， OR < 1）。结论 结论 血吸虫病确诊病例流行病学调查能掌握流行因 素， 有利于进行精细化管理， 促进开展科学防治。

关键词: 血吸虫病； 确诊病例； 流行病学调查； 湖北省