Chin J Schisto Control ›› 2012, Vol. 24 ›› Issue (3): 350-352.

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Progress of research on peroxiredoxin in invertebrates

MA Xian-liang|ZHANG Yi *   

  1. Department of Vector Control|National Institute for Parasitic Diseases|Chinese Center for Disease Control and Prevention|WHO Collaborating Centre for Malaria|Schistosomiasis and Filariasis|Key Laboratory of Pathogenic Parasites and Vector Biology|Ministry of Health|Shanghai 200025| China
  • Online:2012-06-20 Published:2012-06-21
  • Contact: ZHANG Yi

无脊椎动物氧还蛋白过氧化物酶研究进展

马宪亮|张仪*   

  1. 中国疾病预防控制中心寄生虫病预防控制所、 世界卫生组织疟疾、 血吸虫和丝虫病合作中心、 卫生部寄生虫病原与媒介生物学重点实验室 (上海 200025)
  • 通讯作者: 张仪
  • 作者简介:马宪亮|男|硕士研究生。研究方向:病原生物学

Abstract:

Peroxiredoxin(Prx)belongs to a peroxidase family of antioxidant enzymes distributed ubiquitously in aerobic or? ganisms such as yeast,fungi,parasites,mammals and humans. It plays an important role in the defense of reactive oxygen species (ROS)and reactive nitrogen species(RNS)produced by aerobic organisms. This article introduces the classification,mechanism of Prx and the progress of research on Prx in invertebrates.

Key words: Peroxiredoxin; ROS;RNS; Invertebrates

摘要:

氧还蛋白过氧化物酶 (Peroxiredoxin, Prx) 广泛存在于酵母、 真菌、 寄生虫、 哺乳动物和人类等多种生物体, 是过氧化物酶家族重要的抗氧化蛋白之一。Prx可以抵抗生物体内产生的活性氧分子和活性氮分子, 在生物体内起着重要的抗氧化作用。本文综述了Prx的分类、 作用机制, 以及无脊椎动物Prx的研究进展。

关键词: 氧还蛋白过氧化物酶; 活性氧分子; 活性氮分子; 无脊椎动物

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