Abstract: Babesiosis is an emerging parasitic disease, distributed globally in Europe, Asia, Africa, North and South America, and Australia, and the United States is still the country with the largest number of babesiosis cases reported. Babesiosis in China is mainly distributed in the northeast, followed by the southwest and other regions. As a new vector?borne infectious disease, babesiosis poses a serious threat to human health, and its research foundation is relatively weak, so it requires more attention and recognition. The research hot spots on babesiosis are screening of diagnostic antigens, and the mechanisms of Babesia and the hosts, co?infections between Babesia and other pathogens. The epidemic distribution, screening of diagnostic antigens, host immune response mechanism and co?infection of babesiosis in our country and abroad are reviewed in this paper.

Key words: Babesiosis, Epidemic distribution, Diagnostic antigen, Immune response, Co?infection

摘要： 巴贝虫病是一种新发寄生虫病，在全球包括欧洲、亚洲、非洲、南美洲、北美洲及澳洲等地区均有流行，美国是巴贝虫病病例数最多的国家。我国巴贝虫病主要分布在东北地区，其次是西南地区。作为一种新发虫媒传染病，该病对人类健康造成严重威胁，但研究基础相对薄弱，应引起足够重视。巴贝虫病相关研究重点主要包括巴贝虫病诊断抗原筛选、巴贝虫与宿主及其他病原体共感染互作机制。本文就目前国内外巴贝虫病流行分布情况、巴贝虫病诊断抗原筛选、宿主免疫应答机制及共感染现象等研究热点进行综述。

关键词: 巴贝虫病, 流行分布, 诊断抗原, 免疫应答, 共感染