Abstract: (⁃)⁃epigallocatechin⁃3⁃O⁃gallate (EGCG) is the most abundant polyphenol in green tea, which has shown antioxidant, anti⁃inflammatory, anti⁃thrombotic, anti⁃radiation, anti⁃mutant, anti⁃cancer and anti⁃fibrotic actions, and has shown improvements of diabetes, obesity, asthma, cancer, cardiovascular diseases and central nervous system disorders. In addition, EGCG is reported to enhance the human immunity. Recently, EGCG has been found to play a vital role in infectious diseases caused by pathogenic microorganisms, including bacteria, fungi, viruses and parasites. The review summarizes the progress of researches on anti⁃infective properties of EGCG, so as to elucidate the potential role of EGCG in the prevention and treatment of infectious diseases.

Key words: (?)?epigallocatechin?3?O?gallate, Anti?infective activity, Pharmacological action

摘要： 表没食子儿茶素没食子酸酯[(⁃)⁃epigallocatechin⁃3⁃O⁃gallate, EGCG]是绿茶中含量最丰富的多酚类化合物，具有抗氧化、抗炎、抗血栓、抗辐射、抗突变、抗肿瘤、抗纤维化等广泛生物学功能，对糖尿病、肥胖、哮喘、癌症、心血管系统和神经系统疾病等有一定改善和治疗作用，亦可提高机体免疫力。近年来研究发现，EGCG在细菌、真菌、病毒、寄生虫等病原微生物引起的感染性疾病中发挥重要作用。本文就EGCG抗感染特性研究进展进行综述，以揭示其在预防和治疗感染性疾病中的潜在作用。

关键词: 表没食子儿茶素没食子酸酯, 抗感染效果, 药理作用