Abstract: Mosquitoes are the main vectors of many infectious diseases, including malaria and yellow fever, which seriously threaten human health across the world. In addition to the use of chemical insecticides, genetic control is a new attempt to currently available interventions used for mosquito vector control. In terms of ecological safety, however, symbiotic control as a novel approach has been proposed for mosquito control. Since there are multiple symbiotic microflora inhabiting in a variety of tissues of mosquitoes, including the digestive tract, they may affect the transmission of mosquito⁃borne infectious diseases through affecting the lifespan, reproductive competence, and vector competence of the host. In this review, the interactions between symbionts in mosquitoes were summarized, and the research progress of mosquito⁃associated symbionts in the management of mosquito⁃borne infectious diseases was reviewed.

Key words: Mosquito?borne infectious disease, Symbiont, Vector competence, Vector control

摘要： 蚊子作为疟疾、黄热病等传染病的主要传播媒介，严重威胁着全球流行地区的人类健康。目前，蚊媒控制措施除了使用化学杀虫剂外，遗传控制也是一种新的尝试。但考虑到生态安全性，科学家又提出了一种新型控蚊策略——共生控制。由于蚊子体内拥有多种共生菌群，且这些共生菌存在于包括消化道在内的各种组织中，因此可以通过影响宿主的寿命、繁殖能力、媒介能力等来影响蚊媒传染病传播。本文对蚊体内共生菌之间的相互作用进行简述，并对蚊体内共生菌在控制蚊媒传染病中的研究进展进行综述和展望。 　

关键词: 蚊媒传染病, 共生菌, 媒介能力, 媒介控制