Abstract: Objective To analyze the blood supply and metabolism in the marginal area of foci of hepatic alveolar echinococcosis by quantitative perfusion parameters. Methods Thirty patients with hepatic alveolar echinococcosis were scanned with the Revolution CT and the images were analyzed. The perfusion parameters， such as the bloodflow （BF）， time to peak （TTP）， blood volume （BV）， mean transit time （MTT） and hepatic arterial fraction （HAF） were compared among different groups. Results The BF， TTP， BV and MTT values of the peripheral infiltration zone and the values of the surrounding normal liver tissues were significantly different （[F=24.579]， 8.343， 20.535 and 21.843， all P < 0.05）， but the HAF values of the peripheral infiltration zone and the values of the surrounding normal liver tissues were not significantly different in the hepatic alveolar echinococcosis patients （[F=2.621]，P＞0.05）. Conclusion The whole hepatic perfusion Revolution CT can accurately and quantitatively analyze the alveolar echinococcosis foci， especially the peripheral infiltration zone， which has important guiding significance for the formulation of surgical plan.

Key words: Hepatic alveolar echinococcosis, Hepatic perfusion, Marginal infiltration zone, Imaging assessment

摘要： 目的 通过Revolution CT全肝灌注分析肝多房棘球蚴病病灶边缘区域血供及代谢情况。方法 利用Revolution CT对青海省人民医院就诊的30例肝多房棘球蚴病患者行全肝灌注CT扫描并分析图像，比较病灶内、病灶边缘浸润带及周围正常肝组织灌注血流量、达峰时间、血容量、平均通过时间、肝动脉分数值的差异。结果 肝多房棘球蚴病病灶内、病灶边缘浸润带及周围正常肝组织灌注血流量、达峰时间、血容量和平均通过时间差异有统计学意义（F = 24.579、8.343、20.535、21.843，P均 < 0.05），但病灶内、病灶周围浸润带及周围正常肝组织肝动脉分数值差异无统计学意义（F = 2.621，P > 0.05）。结论 Revolution CT全肝灌注能够对肝多房棘球绦虫，尤其是其浸润带进行更精确的定量分析，对肝多房棘球蚴病诊断及手术方案的制定具有重要指导意义。

关键词: 肝多房棘球蚴病, 肝灌注, 边缘浸润带, 影像学评估