Abstract: Objective To understand the disease burden of patients with advanced schistosomiasis in Jiangsu Province. Methods Totally 450 patients with advanced schistosomiasis from southern， northern and central Jiangsu were chosen by the stratified sampling method， and surveyed by the self?designed economic burden questionnaire in 2015. The economic burden of the patients was analyzed by the descriptive analysis method， and its determinants were explored by the multiple linear regression analysis. Results A total of 450 subjects were surveyed and 434 valid questionnaires were recovered with the recovery rate of 96.44%. The per capita economic burden of advanced schistosomiasis patients was 10 217 Yuan in Jiangsu Province in 2015， including 7 221 Yuan in direct economic burden and 2 996 Yuan in indirect economic burden. The average lost labor force time was 140 days for the patients， and was 23 days for the family. The multiple linear regression analysis showed that the marital status， hospitalization health service utilization， and self?reported health score impacted on the disease economic burden. Conclusion The disease burden of patients with advanced schistosomiasis in Jiangsu Province is heavy.

Key words: Advanced schistosomiasis； Disease burden； Economical burden； Medical expense

摘要： 目的 了解江苏省晚期血吸虫病（晚血）患者的经济负担。方法 2015年分层抽取苏南、苏北和苏中地区450例登记在册的晚血患者作为调查对象，自行设计疾病经济负担问卷，对其进行调查。采用描述性分析方法分析晚血患者的经济负担，采用多重线性回归分析探索其影响因素。结果 共发放问卷450份，回收有效问卷434份，问卷回收率为96.44%。2015年江苏省晚血患者人均疾病经济负担为10 217元，其中直接经济负担为7 221元，间接经济负担为2 996元。晚血患者的劳动力损失平均为140 d，家庭成员劳动力损失平均为23 d。多因素分析表明，婚姻状况、是否住院、自身健康状况是晚血疾病经济负担的影响因素。 结论 江苏省晚血患者的疾病经济负担较重。

关键词: 晚期血吸虫病；疾病负担；经济负担；医疗费用