Abstract: Objective To understand the clinical characteristics of newly discovered advanced schistosomiasis patients in Dongpo District, Meishan City, Sichuan Province， so as to provide the reference for enhancing the clinicians’ awareness for diagnosis and treatment of this disease and improving the therapeutic effect. Methods The data of medical records and schedule of case survey of 16 newly discovered advanced schistosomiasis patients in Dongpo District， Meishan City， Sichuan Province were collected and analyzed. Results The mean age of the 16 newly discovered advanced schistosomiasis patients was 63 years， and there were 10 cases at ages of over 60 years. The 16 cases included 8 men and 8 women, and 10 cases were detected in the historical hyper-endemic areas. There were 11 cases with an ascitic type of advanced schistosomiasis， 4 cases with a megalosplenia type， and one case with a colon proliferation type. The primary initial symptoms mainly included ascites, splenomegaly, hypersplenism and portal hypertension. Following inpatient treatments, 15 cases achieved clinical improvments. Conclusions It is necessary to enhance the prevention and control of advanced schistosomiasis. If the patients with portal hypertension， hepatosplenomegaly， upper gastrointestinal hemorrhage visit a doctor， the clinicians should pay much attention to advanced schistosomiasis and they need to comprehensively analyze the clinical data in combination with the epidemiological information， clinical features and laboratory examinations， and make a correct diagnosis and give treatments timely.

Key words: Advanced schistosomiasis； Clinical characteristic； Dongpo District

摘要： 目的 分析四川省眉山市东坡区新发现晚期血吸虫病（晚血）患者的临床特征，为加强临床医生对该病的诊疗意识、及时开展有效救治等提供依据。 方法 收集四川省眉山市东坡区新发现的16例晚血病人住院病历资料、个案调查表等，对比病人省、区两级诊断及复核情况，明确临床诊断及分型。结果 16例新发现晚血病例平均年龄63岁，其中60岁以上者10例；男、女性患者各8例；10例分布在血吸虫病历史重度流行区；腹水型11例，巨脾型4例，结肠增厚型1例。16例新发现晚血病例主要以腹水、脾大、脾功能亢进、门脉高压等为首发临床表现。15例患者经住院治疗后，皆符合临床好转标准。结论 应加强对晚血的防治工作。临床医生对以门脉高压、肝脾肿大、上消化道出血等症状、体征就诊的患者，需结合流行病学史、临床特征、实验室检查等综合分析、判断，及时诊断和治疗。

关键词: 晚期血吸虫病； 临床特征； 东坡区