Abstract: Objective To understand the status of Toxoplasma gondii infections and the awareness of toxoplasmosis prevention and control knowledge among high?risk populations in Hangzhou City. Methods The serum anti?T. gondii antibodies were detected in 100 HIV/AIDS patients， 100 cancer patients， 100 pregnant women and 100 healthy controls， and the awareness of toxoplasmosis prevention and control knowledge was investigated using a questionnaire. Results The sero?prevalence of T. gondii infection was 31%， 30% and 21% in HIV/AIDS patients， cancer patients and pregnant women， which was all significantly higher than in healthy controls （[χ2] = 14.68, 13.96 and 7.56， all P values < 0.01）. The pregnant women had a high awareness rate of toxoplasmosis prevention and control knowledge， and the healthy controls had a low awareness rate. In addition， the subjects had a low awareness rate regarding the questions including “Do you know the damages of Toxoplasma gondii infections?”， “Do you know that consumption of raw or uncooked meat may cause Toxoplasma gondii infections?”， and “Do you know that contact with contaminated soil may cause Toxoplasma gondii infections?”. Conclusions The sero?prevalence of T. gondii infection is high among the high?risk populations in Hangzhou City， including the HIV/AIDS patients， cancer patients and pregnant women， and these high?risk populations have a low awareness rate of some toxoplasmosis prevention and control knowledge. Therefore， it is essential to improve the health education of toxoplasmosis prevention and control knowledge among the high?risk populations， so as to effectively prevent and control human T. gondii infections.

Key words: Toxoplasmosis； High?risk population； Sero?epidemiology； Hangzhou City

摘要： 目的 了解杭州市高危人群弓形虫感染和弓形虫病防治知识知晓情况。方法 采用ELISA方法检测杭州市100例HIV/AIDS患者、100例恶性肿瘤患者、100例孕妇和100例健康对照者血清抗弓形虫抗体，对全部调查对象进行弓形虫病防治知识问卷调查。结果 HIV/AIDS、恶性肿瘤患者和孕妇血清抗弓形虫抗体阳性率分别为31%、30%和21%，均显著高于健康对照者的5%（[χ2] = 14.68, 13.96和7.56，[P均< 0.01]）。孕妇对弓形虫病防治知识的知晓率整体较高，健康对照者对弓形虫病防治知识的知晓率整体较低；调查对象对“你知道弓形虫感染的危害吗？”、“你知道生食或食用未煮熟的肉类会感染弓形虫吗？”和“你知道接触被污染的土壤会感染弓形虫吗？”等问题的知晓率较低。结论 杭州市HIV/AIDS、恶性肿瘤患者和孕妇等高危人群弓形虫感染率较高，且对部分弓形虫病防治知识知晓率较低。有必要加强对高危重点人群的弓形虫病防治知识健康教育，有效预防和控制弓形虫感染。 ［关键词］　

关键词: 弓形虫病；高危人群；血清流行病学；杭州市