Abstract:

Clonorchis sinensis infection is carcinogenic to human， which results in cholangiocarcinoma， confirmed by the World Health Organization. An investigation in 2005 indicated that the standardized C. sinensis infection rate was 0.58%， with 12 490 000 infected people estimated in the clonorchiasis endemic areas in China. In the world， 80% of C. sinensis infected people were distributed in China. Diagnostic Criteria for Clonorchiasis （WS309-2009） was compiled by the ex?Ministry of Health of the People’s Republic of China and it was issued and implemented in March 13， 2009. The Diagnostic Criteria for Clonorchiasis is composed of six chapters， including the Range of Application， Terms and Definitions， Diagnostic Basis， Diagnostic Principle， Diagnostic Standard， and Differential Diagnosis. Three informative appendices （etiology， epidemiology， clinical manifestation； enzyme?linked immunosorbent assay； differential diagnosis） and one normative appendix （laboratory examination） are appended. The Criteria provides the technical reference for diagnosis of clonorchiasis in medical institutions and disease control institutions. Combined with the current epidemic situation of clonorchiasis in China， this paper interprets the main contents of the Diagnostic Criteria for Clonorchiasis （WS309-2009）， so as to promote its learning and implementing.

Key words: Clonorchiasis； Diagnosis； Criteria

摘要： 华支睾吸虫是被世界卫生组织确认的胆管癌Ⅰ类致癌物。2005年调查显示，我国华支睾吸虫病流行区的标化感染率为0.58%，估算感染人数为1 249万人，且全球华支睾吸虫感染者中有80%分布在中国大陆。原国家卫生部卫生政策法规司于2009年3月13日颁布实施了《华支睪吸虫病诊断标准》（WS309-2009）。该标准由6章组成，包括适用范围、术语和定义、诊断依据、诊断原则、诊断标准和鉴别诊断。另附有3个资料性附录（病原学、流行病学和临床表现、酶联免疫吸附试验及鉴别诊断）和1个规范性附录（病原学检查）。该标准的颁布施行，为全国各级医疗机构和疾病预防控制机构诊断华支睾吸虫病提供了技术规范。本文结合我国华支睪吸虫病的流行情况，对《华支睪吸虫病诊断标准》（WS309-2009）的主要内容进行了解读，以促进该标准的宣传贯彻和实施。

关键词: 华支睾吸虫病；诊断；标准