Abstract: Objective To evaluate the molluscicidal effect of suspension concentrate of niclosamide ethanolamine salt （SCNE） against Oncomelania hupensis snails in laboratory and field. Methods The experiment of SCNE against the snails by using the immersing and spraying methods was performed in laboratory and field， with control groups of wettable powder of niclosamide ethanolamine salt （WPN）. Results In the laboratory， LC50（s） of SCNE for 24， 48 h and 72 h by using the immersion method were 0.092 6， 0.062 9 mg/L and 0.054 9 mg/L， respectively. The mortality rates of snails for 24， 48 h and 72 h by using the immersion method were all 100％ with the concentrations of 0.25 mg/L. The mortality rates of snails were all 100% while spraying SCNE for 3 d in the laboratory with the concentrations of 0.25 g/m2. In Jiangling County， except 0.5 g/m3 SCNE immersing the snails for 24 h， the mortality rates of snails by using SCNE with the immersing method were all 100％. While the concentration of SCNE was 0.5 g/m3 or above， the mortality rates were all 100％ after the use of it with the immersion method for 2 d in Gong’an County. In Jiangling County， the mortality rates of snails by using SCNE 0.5 g/m3 for 1 d， 3 d， and 7 d with the spraying method were 87.5％， 92.82% and 97.40% respectively. While the concentration of SCNE was 0.5 g/m3， the mortality rates were 85.94％， 86.78％ and 94.21％ respectively after the use of it with the spraying method for 1 d， 3 d， 7 d in Gong’an County， and the molluscicidal effect of SCNE （1.0 g/m2） was higher than that of WPN. Conclusion SCNE has a high molluscicidal effect in the laboratory and field， and it is a novel and simple formulation of niclosamide.

Key words: Suspension concentrate of niclosamide ethanolamine salt （SCNE）； Wettable powder of niclosamide ethanolamine salt （WPN）； Molluscicidal effect； Oncomelania hupensis snail

摘要： 目的 评价50%杀螺胺乙醇胺盐悬浮剂的实验室和现场杀螺效果。 方法 在实验室和现场采用50%杀螺胺乙醇胺盐悬浮剂浸杀、喷洒法灭螺，并与50％氯硝柳胺乙醇胺盐可湿性粉剂进行效果比较。结果 室内浸杀，50%杀螺胺乙醇胺盐悬浮剂24、48 h和72 h LC50值分别为0.092 6、0.062 9 mg/L和0.054 9 mg/L；室内0.25 mg/L浸杀24、48 h和72 h，钉螺死亡率均为100％；室内喷洒，0.25 g/m2 3 d后钉螺死亡率即可达100％。江陵现场，除0.5 g/m3浸杀24 h钉螺死亡率为96.67%外，其余浓度组钉螺死亡率均为100%。公安现场，0.5 g/m3及以上浓度组浸杀钉螺2 d后，钉螺死亡率可达100％；江陵现场，0.5 g/m2喷洒1、3 d和7 d后钉螺死亡率分别为87.5％、92.82%和97.40%。公安现场，0.5 g/m2喷洒1、3 d和7 d后钉螺死亡率分别为85.94％、86.78％和94.21％，且1.0 g/m2组钉螺死亡率均高于实验对照组WPN。结论 50%杀螺胺乙醇胺盐悬浮剂具有较好的实验室和现场杀螺效果，为新型高效、使用方便的灭螺药物剂型。

关键词: 杀螺胺乙醇胺盐；氯硝柳胺乙醇胺盐可湿性粉剂；杀螺效果；钉螺