Chin J Schisto Control ›› 2017, Vol. 29 ›› Issue (3): 385-387.

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Progress and application of immunodiagnostic methods of giardiasis

ZHANG Le-sheng1|2| WANG Yan-juan1| CAO Jian-ping1*   

  1. 1 National Institute of Parasitic Diseases| Chinese Center for Disease Control and Prevention; Key Laboratory of Parasite and Vector Biology| Ministry of Health; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases| Ministry of Science and Technology| Shanghai 200025| China;2 Anhui Institute of Schistosomiasis Control| China
  • Online:2017-06-20 Published:2017-06-20
  • Contact: CAO Jian?ping

贾第虫病免疫学诊断方法及其应用研究进展

章乐生1|2|王燕娟1|曹建平1*   

  1. 1 中国疾病预防控制中心寄生虫病预防控制所、卫生部寄生虫病原与媒介生物学重点实验室、世界卫生组织热带病合作中心、科技部国家级热带病国际联合研究中心(上海 200025);2 安徽省血吸虫病防治研究所
  • 通讯作者: 曹建平
  • 作者简介:章乐生|男|硕士研究生|主管技师。研究方向:寄生虫病诊断
  • 基金资助:
    国家公益性卫生行业科研专项(201502021);国家重点研发计划(2016YFC1201900)和上海市公共卫生第四轮三年行动计划(15GWZK0101、GWIV?29)

Abstract: Giardia lamblia is an important intestinal protozoan which can cause diarrhea in humans. The detection of Giardia infection is performed through the detection methods of pathogen, immunoassay and molecular biology. Currently, the immunodiagnostic methods have good application and development prospect because of high sensitivity and specificity, simple and convenient, and time saving. In this article, we review the main progress and application of immunodiagnostic methods for Giardia infection.

Key words: Giardiasis; Immunodiagnosis; Counterimmunoelectrophoresis; Western blotting; Immunofluorescence technique; Enzyme?linked immunosorbent assay; Immunochromatographic test

摘要: 蓝氏贾第鞭毛虫(简称贾第虫)是一种重要的肠道致病原虫,人体感染后可引起腹泻等症状。目前,贾第虫感染诊断主要有病原学、免疫学及分子生物学等方法;其中免疫学诊断技术因快速、简便、敏感性高、特异性强等优点,具有良好的应用前景。本文主要就常用贾第虫感染免疫学诊断技术及其应用情况作一综述。

关键词: 蓝氏贾第鞭毛虫病;免疫诊断;对流免疫电泳;免疫印迹法;免疫荧光技术;酶联免疫吸附试验;免疫层析法

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