Chin J Schisto Control ›› 2017, Vol. 29 ›› Issue (3): 352-354.

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Survey on Toxoplasma gondii infection among key populations in Wuxi City

GAO Dong-lin| MENG Xiao-jun△*| ZHANG Xuan| QIAN Yan-hua| LU Bing   

  1. Wuxi Center for Disease Control and Prevention| Jiangsu Province| Wuxi 214023| China
  • Online:2017-06-20 Published:2017-06-20
  • Contact: MENG Xiao?jun

无锡市重点人群弓形虫感染状况调查

高东林|孟晓军△*|张轩|钱燕华|陆兵   

  1. 江苏省无锡市疾病预防控制中心(无锡214023)
  • 通讯作者: 孟晓军
  • 作者简介:高东林|男|本科|主治医师。研究方向:寄生虫病监测与传播风险评估
  • 基金资助:
    无锡市科技局科技专项重点项目(CSE31N1407)

Abstract: Objective To investigate the prevalence and risk factors of Toxoplasma gondii infection among key populations in Wuxi City, Jiangsu Province, so as to provide evidences for developing preventive and control interventions for T. gondii infection. Methods A questionnaire was designed to conduct face?to?face interviews to HIV/AIDS carriers/patients, tumor patients, pregnant women and pet breeders. The blood samples were collected to test anti?Toxoplasma IgM and IgG antibodies by using ELISA method. Results Totally 404 participants were investigated, and 38 were positive in testing T. gondii antibodies (9.4%), and among these, 37 (97.4%) were IgG positive and 1 (2.6%) was IgM positive. The multivariate logistic regression indicated that age, regularly contacting cats/dogs and being HIV positive were associated with the infection of T. gondii (OR=2.1, 2.6 and 2.3, all P < 0.05). Breeding pets, being HIV positive and being tumor patients were more likely to infect T. gondii than being pregnant (OR = 1.5, 8.1 and 2.8, all P < 0.05). Conclusion The high infection rate of T. gondii is observed among key populations in Wuxi City, so that the effective measurements should be taken to enhance the intervention among key populations including immunocompromised people, pet breeders or people having bad dietary habits of eating raw food.

Key words: Toxoplasma gondii; Infection rate; Influencing factor; Wuxi City

摘要: 目的 了解无锡市重点人群弓形虫感染状况及其影响因素,为制定科学的防治措施提供依据。 方法 选取无锡市城区艾滋病病毒感染者/病人、肿瘤病人、孕妇、宠物饲养者4类人群为调查对象开展问卷调查,并采血用ELISA法检测抗弓形虫IgG、IgM抗体。 结果 共调查404人,弓形虫抗体阳性38人,总阳性率为9.4%;其中IgG阳性37人,占97.4%;IgM阳性1人,占2.6%。多因素分析结果表明年龄、生食食物等不良饮食习惯和接触猫/狗是弓形虫感染的影响因素(OR = 2.1、2.6和2.3,P均< 0.05)。宠物饲养者、HIV/AIDS和肿瘤病人比孕妇更易感染弓形虫(OR =1.5、8.1和2.8,P均< 0.05)。 结论 无锡市重点人群弓形虫感染率较高,需要采取针对性措施,加强对免疫缺陷、有不良饮食习惯及宠物饲养者等人群的干预工作。

关键词: 弓形虫;感染率;影响因素;无锡市

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