Chin J Schisto Control ›› 2017, Vol. 29 ›› Issue (1): 53-58.

Previous Articles     Next Articles

Epidemic status of alveolar echinococcosis in Tibetan children in south Qinghai Province

HAN Xiu-min1*| ZHANG Xue-yong2| CAI Qi-gang2| ZHANG Jing-ni1| WANG Yong-shun3| ZHANG Qiang1   

  1. 1 Qinghai Provincial People’s Hospital| Qinghai Province| Xining 810007| China; 2 Qinghai Academy of Animal Science and Veterinary Medicine| Qinghai University| China; 3 Qinghai Provincial Institute of Endemic Disease Prevention and Control| China
  • Online:2017-02-23 Published:2017-02-24

青海省南部高原藏族儿童泡型包虫病流行现状分析

韩秀敏1*|张学勇2|蔡其刚2|张静妮1|王永顺3|张强1   

  1. 1青海省人民医院(西宁810007);2青海大学青海省畜牧兽医科学院;3青海省地方病预防控制所
  • 作者简介:韩秀敏|女|硕士|研究员。研究方向:寄生虫病预防控制
  • 基金资助:
    青海省科技基础研究计划项目(2016?ZJ?791)

Abstract: Objective To understand the epidemic status of alveolar echinococcosis in Tibetan children in south Qinghai Province. Methods The imageology and serology methods were applied to investigate the epidemic status of alveolar echinococcosis of elementary school students in Yushu and Guoluo prefectures. Results Totally 19 629 children were investigated by the portable B ultrasound and 221 children were diagnosed as alveolar echinococcosis with the morbidity of 1.13%. Totally 9 888 were investigated by the indirect ELISA, and the positive rate of serum tests was 12.59% (190/9 888). The total morbidity of alveolar echinococcosis of children in Yushu Prefecture was 0.42% (31/7 454) and it was 1.57% (190/12 175) in Guoluo Prefecture and there was a significant difference between them ([χ2]= 53.42, P<0.005). The sero?positive rates of children in Yushu and Guoluo were 4.26% (302/7 081) and 18.56% (1 835/9 888), respectively ([χ2]= 765.77, P<0.005). The counties with the highest prevalence of alveolar echinococcosis in children were Dari County (4.31%, 106/2 461) and Banma County (1.92%, 26/1 351) of Guoluo Prefecture, and Chengduo County (1.11%, 18/1 612) of Yushu Prefecture. The total morbidity rates of alveolar echinococcosis of male and female children were 0.91% (91/9 954) and 1.34% (130/12 175) respectively ([χ2]= 7.35, P<0.005). The total sero?positive rates of alveolar echinococcosis of male and female children were 12.10% (1 037/8 568) and 13.09% (1 100/8 406) respectively ([χ2]= 3.63, P>0.05). The total morbidity of alveolar echinococcosis of children in different age groups was from 1.00% to 1.13%, and there was no significant difference among the age groups ([χ2]=2.73, P>0.05). The P1a type, P1b type and P2 type accounted for 67.76% (145/214), 10.75% (23/214) and 16.36% (35/214) respectively among the alveolar echinococcosis patients. The diameters of nidus of 87.38% (187/214) patients were less than 5 cm, and 2.80% (6/214) were more than 10 cm. Conclusions The epidemic status of alveolar echinococcosis of Tibetan children in south Qinghai Province is serious, but most of the patients were at early stage of the disease. The screening work of alveolar echinococcosis should be strengthened in Tibetan children, so as to perform the early diagnosis and treatment.

Key words: Qinghai?Tibet plateau; Child; Alveolar echinococcosis; Prevalence; Morbidity; Sero?positive rate

摘要: 目的 调查青海藏区高原的藏族儿童泡型包虫病的流行情况。 方法 采用影像学和血清学方法对玉树州、果洛州在校小学生开展泡型包虫病流行情况调查。 结果 B超共调查儿童19 629人,泡型包虫病总患病率为1.13%(221例);血清学调查9 888人,总阳性率为12.59% (190例)。玉树州和果洛州儿童泡型包虫病总患病率分别为0.42% (31/7 454)、1.57% (190/12 175),差异有统计学意义([χ2]= 53.42,P<0.005);血清学阳性率分别为4.26%(302/7 081)、18.56%(1 835/9 888),差异有统计学意义([χ2]= 765.77,P<0.005)。儿童患病率最高的3个县为果洛州的达日县4.31%(106/2 461)、班玛县1.92%(26/1 351)和玉树州的称多县1.11%(18/1 612)。男童和女童泡型包虫病总患病率分别为0.91% (91/9 954)、1.34% (130/12 175),差异有统计学意义([χ2]= 7.35,P<0.005);男童和女童血清学总阳性率为12.10%(1 037/8 568)、13.09% (1 100/8 406),差异无统计学意义([χ2]= 3.63,P>0.05)。不同年龄组间儿童患病率差异无统计学意义([χ2]= 2.73,P>0.05)。泡型包虫病患者P1a型占67.76%(145/214),P1b型占10.75% (23/214)、P2型占16.36%(35/214)。患者病灶直径<5 cm者占87.38%(187/214),>10 cm者仅占2.80%(6/214)。 结论 青海南部藏区高原儿童存在泡型包虫病的严重流行,但多数患者为泡型包虫病早期,应加大儿童泡型包虫病的筛查力度,及早进行诊断和治疗。

关键词: 泡型包虫病;儿童;流行;患病率;血清学阳性率;青藏高原

CLC Number: