Abstract: Objective Objective To improve the curative effect of advanced schistosomiasis patients with ascites and HBV infection. Methods Methods A total of 27 advanced schistosomiasis patients with ascites and HBV infection were selected as a trial group and giv? en with anti?HBV treatment，and 31 corresponding patients were as the controls and did not received anti?HBV treatment from February 2003 to December 2012. Results Results The incidence of ascites recurrence，spontaneous peritonitis，hepatic encephalopa? thy，hepatorenal syndrome，upper gastrointestinal bleeding，and primary liver cancer in the trial group were significantly lower than those in the control group. The detection indexes of liver function，renal function and prothrombin time in the trial group were superior to those in the control group. The mortality in the treatment group was also significantly lower than that in the con? trol group. Conclusion Conclusion The anti?HBV treatment in the advanced schistosomiasis patients with ascites and HBV infection can obviously improve their physical conditions，the survival rate，and their life qualities.

Key words: Advanced schistosomiasis； Ascites； HBV； Anti?HBV treatment

摘要： 目的 目的 提高晚期血吸虫病 （晚血） 合并HBV感染患者抗病毒治疗的疗效， 减少并发症， 提高生活质量。方法 方法 选择2003年2月至2012年12月在作者所在医院行抗病毒治疗的27例腹水型晚血合并HBV感染患者作为治疗组， 对其 抗HBV治疗的临床及随访资料进行回顾性分析； 同时以31例未作抗乙肝病毒治疗、 病情基本相同的腹水型晚血合并 HBV感染患者作为对照。结果 结果 治疗组自发性腹膜炎、 肝性脑病、 肝肾综合征、 上消化道出血、 原发性肝癌的发生率明 显低于对照组， 肝功能、 肾功能、 凝血酶原时间检测指标明显优于对照组， 死亡率明显低于对照组。结论 结论 腹水型晚期血 吸虫病合并HBV感染患者通过抗病毒治疗， 可明显改善患者愈后， 提高患者生存率。

关键词: 晚期血吸虫病； 腹水型； HBV； 抗病毒治疗