Abstract: Objective Objective To analyze the epidemiologic feature of overseas imported malaria in order to provide the evidence for improving the surveillance and control of malaria in Wuhan City. Methods Methods The epidemiological investigation data of overseas imported malaria cases were collected and analyzed with an epidemiological method including plasmodium species，epidemic fo? cus distribution，domestic distribution，population characteristics，attack?diagnosis interval，clinical grading，etc. in Wuhan City from 2008 to 2013. Results Results A total of 240 overseas imported malaria cases were reported，including 180 cases from Afri? can countries and the proportion of Plasmodium falciparum infections was 82.22%，and 60 cases from Southeast Asian coun? tries and the proportion of Plasmodium vivax infections was 76.67%，and the proportions of the parasite species were significant? ly different between the two regions（χ2 =105.53，P＜0.001） . The male and young adults were dominant. there were no statisti? cal significance between clinical grading and attack?diagnosis interval（Z=-0.99， P = 0.32），vocational background（ χ2 = 10.61， P=0.10），then clinical symptoms aggravated the situation was occurred more easily among the first attack cases（χ2 = 7.66， P＜0.05）and the falciparum malaria cases（χ2 =24.27， P＜0.001） . Conclusions Conclusions The overseas imported malaria cases are increasing rapidly with years and the malignant malaria cases were more than other malaria cases in Wuhan City. Therefore， the surveillance and management of the returnees from malaria endemic areas should be strengthened continually.

Key words: Malaria； Imported case； Epidemiology

摘要： 目的 目的 分析武汉市国外输入性疟疾的流行病学特征， 为疟疾监测和防控提供科学依据。方法 方法 收集武汉市 2008-2013年国外输入性疟疾病例流行病学资料， 对感染疟原虫虫种、 疫源地分布、 地区分布、 人群特征、 发病?诊断时间、 临床分度等进行流行病学分析。结果 结果 2008-2013年武汉市共报告国外输入性疟疾240例。来自非洲国家180例， 其中 恶性疟占82.22%； 来自东南亚国家60例， 其中间日疟占76.67%， 两地区输入性病例的疟原虫虫种构成比不同 （χ2 = 105.53， P＜0.001）。输入性疟疾病例以出国务工的青壮年男性为主。不同临床分度的发病?诊断时间、 不同职业的临床 分度差异均无统计学意义 （Z=-0.99， P=0.32、χ2 =10.61， P = 0.10）； 疟疾初发病例较有疟史者 （χ2 =7.66， P＜0.05）、 恶性 疟较非恶性疟更易出现临床症状加重 （χ2 =24.27， P＜0.001）。结论 结论 武汉市国外输入性疟疾病例逐年增多， 且以恶性 疟为主， 应加强防控及出回国人员的管理工作。

关键词: 疟疾； 输入性； 流行病学