Chin J Schisto Control ›› 2014, Vol. 26 ›› Issue (5): 568-.

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Research progress of immunoregulation of B cells to schistosome infection

TANG Hong-bin1 | DONG Hui-fen2* |JIANG Ming-sen2*   

  1. 1 Center for Animal Experiment of Wuhan University|Hubei Province|Wuhan 430071|China;2 Department of Medical Parasi? tology| School of Basic Medical Science of Wuhan University| China
  • Online:2014-10-27 Published:2014-10-27
  • Contact: DONG Hui?fen,JIANG Ming?sen

B细胞免疫调节血吸虫感染的研究进展

汤宏斌1|董惠芬2*|蒋明森2*   

  1. 1武汉大学动物实验中心 (武汉430071); 2武汉大学基 础医学院人体寄生虫学教研室
  • 通讯作者: 董惠芬,蒋明森
  • 作者简介:汤宏斌| 男| 博士。研究方向: 动物感染免疫与发育
  • 基金资助:
    国家自然科学基金 (30872202)

Abstract: Recent studies found that B cell subsets and their factors have double effects on anti? and aiding schistosome infec? tion. This article summarizes the research progress of positive and negative immunoregulation of schistosome infection involving B lymphocytes, antibody and regulatory B cells(Bregs)relating cytokines(IL?10,IL?7 and TGF?β) .

Key words: Schistosome infection; B lymphocytes; Immunoregulation

摘要: 近年的研究发现, B细胞亚群及其相关因子在抗血吸虫感染和促进感染方面发挥了双重作用。本文综述了血 吸虫感染过程中, B细胞及其产生的抗体和调节性B细胞相关细胞因子——IL?10、 IL?7、 TGF?β进行正负免疫调控的研究 进展。

关键词: 血吸虫感染; B淋巴细胞; 免疫调控

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