Abstract: The larval and adult schistosomes can effectively establish the stable parasitic relationship with their final hosts and then maintain the parasitism for a long time，due to the successful adaptation to their parasitic lifestyle. This paper reviews the progress of research on parasitic adaptability of schistosomes in several respects，and demonstrates the application value of schisto? somal genes related to parasitic adaptability in schistosomiasis control and exploitation of natural active molecules.

Key words: Schistosome； Parasitic adaptability； Co?evolution；Target；Natural active molecule

摘要： 血吸虫的尾蚴和成虫能快速建立并长期维系与终末宿主的寄生关系， 源自于其对寄生生活方式的高度适应性。 本文概述了血吸虫寄生适应性多个方面的研究进展， 并简要介绍其因寄生性适应而进化出的功能基因在血吸虫病防治靶 标发掘方面以及其天然活性分子在多种应用方面的价值。

关键词: 血吸虫； 寄生适应性； 协同进化； 靶标； 天然活性分子