Abstract: Objective To explore a surgical treatment of advanced schistosomiasis with cavernous transformation of the portal vein. Method The clinical data of 18 patients who suffered from advanced schistosomiasis with cavernous transformation of the portal vein were collected and analyzed retrospectively in the Affiliated Xiangyue Hospital of Hunan Institute of Parasitic Diseases. Results Two cases were undertaken the endoscopic variceal ligation，and the upper gastrointestinal bleeding happened 32 months and 40 months after the treatment respectively，and they received the splenectomy and esophagogastric devascularization again；16 cases were undertaken the splenectomy and esophagogastric devascularization. During the follow?up of 6-72 months，no esophageal and gastric varices were found. Conclusion Splenectomy and esophagogastric devascularization is effective in the treatment of advanced schistosomiasis with cavernous transformation of the portal vein.

Key words: Advanced schistosomiasis；Cavernous transformation of the portal vein（CTPV）；Esophagogastric devasculariza? tion

摘要： 目的 目的 探讨晚期血吸虫病门静脉高压症合并门静脉海绵样变的外科治疗方式。 方法 方法 对湖南省血吸虫病防治 所附属湘岳医院18例晚期血吸虫病合并门静脉海绵样变患者的临床资料进行回顾性分析。结果 结果 16例患者行脾切除贲 门周围血管离断术； 2例患者先行内镜食管曲张静脉套扎术， 后因再次食管静脉曲张破裂出血， 分别于术后32、 40个月行脾 切除贲门周围血管离断术。术后随访6～72个月， 未再发现食管胃底静脉曲张。结论 结论 脾切除贲门周围血管离断术适用 于晚期血吸虫病门静脉高压合并门静脉海绵样变的治疗。

关键词: 晚期血吸虫病； 门静脉海绵样变； 贲门周围血管离断术