Abstract: Antibody has extensive application prospects in the biomedical field. The inherent disadvantages of traditional poly? clonal antibody and monoclonal antibody limit their application values. The humanized and fragmented antibody remodeling has given a rise to a series of genetic engineered antibody variant. This paper reviews the progress of research on genetic engineering antibody and its application in prevention and control of parasitic diseases.

Key words: Antibody； Genetic engineering；Antibody fragment； Parasitic disease

摘要： 抗体在生物医学领域具有广泛的应用前景。传统多克隆抗体及单克隆抗体由于其固有的缺点使其应用价值受 到限制。抗体的人源化与片段化改造催生出一系列基因工程抗体变体。本文就基因工程抗体及其在寄生虫病防治中的 应用研究进展作一综述。

关键词: 抗体； 基因工程； 抗体片段； 寄生虫病