Abstract: Objective To assess the molluscicidal effect and cost?effectiveness of suspension concentrate of metaldehyde and niclosamide（MNSC）in the field，so as to evaluate the possibility of popularization and application value. Methods 26% MNSC and 50% wettable powder of niclosamide（WPN）were used for Oncomelania snail control with the spraying method in the field， and the 15?d molluscicidal effects and costs were investigated. Results Fifteen days after the spraying，in the beach of Dongjing River，the snail death rates of MNSC and WPN were 89.40% and 88.08%，respectively，and the density reduction rates of MNSC and WPN were 92.35% and 91.67%，respectively. In the marshland of Honghu Lake，the snail death rates of MNSC and WPN were 86.59% and 87.01%，respectively，and the density reduction rates of MNSC and WPN were 90.05% and 91.71%，respective? ly. There was no significant difference in the molluscicidal effect between two drugs（P > 0.05） . The cost of MNSC used in 100 m2 was 15.03 Yuan，while the cost of WPN used in 100 m2 was 16.29 Yuan. Conclusion MNSC has high molluscicidal efficacy， low cost and low impact on environments，which possesses of popularization and application value in the field.

Key words: Oncomelania hupensis；Suspension concentrate of metaldehyde and niclosamide（MNSC）；Molluscicidal effect； Cost?effectiveness

摘要：

目的 了解26%四聚杀螺胺悬浮剂 （MNSC） 现场灭螺效果和应用成本， 评价其推广应用价值。 方法 选择河滩和湖滩为试验现场， 评价MNSC喷洒法灭螺效果与使用成本； 设50%氯硝柳胺乙醇胺盐可湿性粉剂 （WPN） 作为对照。结果 喷洒MNSC后15 d， 河滩钉螺死亡率为89.40%， 钉螺密度下降了92.35%； WPN组钉螺死亡率为88.08%， 钉螺密度下降了91.67%。在湖滩， MNSC组钉螺死亡率为86.59%， 钉螺密度下降了90.05%； WPN组钉螺死亡率为87.01%， 钉螺密度下降了91.71%。2个试验现场2种药物杀螺效果差异均无统计学意义 （P均＞0.05）。MNSC 每应用100 m2 的综合成本为15.03 元， WPN每应用100 m2 的综合成本为16.29元。结论 MNSC杀螺效果好、 使用成本低、 对环境影响小， 是一种值得推广应用的杀螺药物。

关键词: 钉螺； 四聚杀螺胺悬浮剂； 杀螺效果； 效果?成本分析