Abstract:

As the only intermediate host of Schistosoma japonicum，the control of Oncomelania snails serves as a major part in
schistosomiasis control. This review mainly demonstrates the following aspects：the invasion of schistosome miracidium into
snails，the mechanism of resistance to miracidia，and the factors influencing this process. With a view to explore the methods of in?
terrupting every phase during miracidium infection，this article focuses on the possibility for safeguarding human health through
protecting snails，namely，achieving snails harmlessness.

Key words: Oncomelania snail；Schistosome；Miracidium；Interplay

摘要：

钉螺是日本血吸虫的唯一中间宿主，消灭和控制钉螺是控制血吸虫病的一个重要环节。本文主要从日本血吸虫毛蚴入侵钉螺的机制、钉螺对血吸虫幼虫的抵抗机理，以及影响此过程的因素等几个方面进行综述，探索在毛蚴感染钉螺的各个环节进行阻击，通过先保护钉螺使其不受血吸虫感染（即钉螺无害化）而最终保护人类的方法。

关键词: 钉螺；血吸虫；毛蚴；相互作用