Chin J Schisto Control ›› 2012, Vol. 24 ›› Issue (5): 557-558.

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Preventive effect of plant cercaricide Fangyouling for schistosome infection

  

  1. 1 School of Public Health|Wuhan University|Wuhan 430072|China;2 Quzhou Municipal Center for Disease Control and Preven? tion, Zhejiang Province, China;3 Hubei Institute of Schistosomiasis Control|China
  • Online:2012-10-11 Published:2012-10-11
  • Supported by:

    国家高技术研究发展计划(863计划)(2004AA2Z3600)

植物提取液防蚴灵预防血吸虫感染效果

王圣贤1|2|施佳敏1|曹慕民3|代凌峰3|戴裕海3*   

  1. 1武汉大学公共卫生学院(武汉430079);2 浙江省衢州市疾病预防控制中心;3 湖北省血吸虫病防治研究所
  • 作者简介:王圣贤|男|硕士研究生。研究方向:血吸虫病防治管 理

Abstract:

Objective To evaluate the preventive effect of Fangyouling(a plant cercaricide)for schistosome infection in the field. Methods Villagers contacting schistosome infested water in 3 administrative villages in Hubei Province were randomly se? lected,and the villagers rubbing Fangyouling before they contacted with the infested water were divided into Group Ⅰ(159 cases) and those not rubbing Fangyouling before they contacted with the infested water were divided into Group Ⅱ(172 persons). All the villagers were investigated by questionnaire,and their infections of schistosome were tested by sera and fecal examinations. Re? sults There were no differences of constituent ratios of gender,age,occupation,time and type of infested water contact between the two groups(all P values>0.05). The positive rates of sera and fecal examinations were 3.14% and 1.87%,respectively in Group Ⅰ,and the positive rates of sera and fecal examinations were 9.30% and 6.40%,respectively in Group Ⅱ,and there were significant differences between both the results of sera and fecal examinations of GroupⅠand Group Ⅱ(both P values < 0.05). In Group Ⅰ,there were 110 people who completely embrocated Fangyouling,and their positive rates of sera and fecal examinations were 0.91% and 0,respectively. There are 42 people who incompletely embrocated Fangyouling,and their positive rates of sera and fecal examinations were 8.16% and 6.12%,respectively,and there were significant differences(both P values < 0.05). Con? clusions The preventive effect of schistosome infection of Fangyouling is significant. Incomplete embrocating may be one of the possible reasons for people still being infected with schistosome after rubbing the protective agent.

Key words: Schistosomiasis;Fangyouling;Preventive effect

摘要:

目的评估植物提取液“防蚴灵”预防血吸虫感染的效果。方法随机抽取湖北省3个行政村因生产、生活接触疫水的村民作为研究对象,将接触疫水前涂擦“防蚴灵”的村民作为Ⅰ组,未涂擦“防蚴灵”的村民作为Ⅱ组,对两组进行问卷调查,并进行血检和粪检以了解其血吸虫感染情况。结果两组性别、年龄、职业以及疫水接触方式构成均无统计学差异(P均>0.05)。Ⅰ组159人,血检阳性率3.14%,粪检阳性率1.87%,Ⅱ组人员血检阳性率9.30%,粪检阳性率6.40%,差异均有统计学意义(P均< 0.05)。Ⅰ组中完全涂擦“防蚴灵”110人,血检阳性率0.91%,粪检结果阳性率为0,不完全涂擦“防蚴灵”42人,血检阳性率8.16%,粪检阳性率为6.12%,差异均有统计学意义(P均< 0.05)。结论“防蚴灵”预防血吸虫感染效果明显;接触疫水前涂擦“防蚴灵”不完全可能是涂擦防护剂但仍出现人员感染的原因之一。

关键词: 血吸虫病;防蚴灵;防护效果

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