Abstract:

Angiostrongylus cantonensis is a lung worm of rat（definitive host） . Human，an abnormal host，can acquire the in? fection by ingesting food containing the infective larvae of this worm（third?stage larvae） . Although the larvae cannot develop into adult worm in human body，it moves to human brain and eyes，causing eosinophilic meningitis（EM），meningoencephalitis， or oc? ular angiostrongyliasis（OA） . Here we review papers related to Angiostrongylus cantonensis and angiostrongyliasis cantonensis which were published in recent ten years，and identify the main institutes and principal investigators（PI）who are researching An? giostrongylus cantonensis. We also outline the advances in research on pathogen biology，pathogenesis，diagnostic techniques，epi? demiology and prevention，as well as drug developed against Angiostrongylus cantonensis.

Key words: Angiostrongylus cantonensis； Angiostrongyliasis cantonensis； Pubmed；Review

摘要：

广州管圆线虫是一种寄生于鼠肺动脉系统的蠕虫， 人类是其非正常宿主， 因生食含有广州管圆线虫III期幼虫的螺肉而感染。幼虫侵入人体后， 进入中枢神经系统可引起嗜酸性粒细胞增高性脑膜炎、 嗜酸性粒细胞增高性脑炎或眼部广州管圆线虫病。本综述通过对PubMed中有关广州管圆线虫及广州管圆线虫病的文献进行检索， 着重分析了近10年来有关广州管圆线虫及广州管圆线虫病的研究概况， 对广州管圆线虫病原学、 致病机制、 诊断技术、 治疗药物及方案、 流行病学和预防等方面进行了阐述。

关键词: 广州管圆线虫； 广州管圆线虫病； PubMed； 综述