Abstract:

Objective To understand the co?infection status of HIV and intestinal parasites in a HIV/AIDS highly endemic ar? ea in China. Methods A cross?sectional survey was carried out in two villages in Fuyang City，Anhui Province，and the infection status of HIV and intestinal parasites were investigated by blood and fecal examinations. Results A total 769 individuals were en? rolled in the investigation，and 720 of whom were participated in stool examinations for intestinal parasite infections. The infection rates of parasites were as follows：0.56% for Ascaris lumbricoides，4.03% for Hookworm，0.28% for Trichuris trichiura，0.42% for Clonorchis sinensis，21.39% for Blastocystis hominis，3.89% for Giardia lamblia，1.67% for Entamoeba spp.，4.44% for Cryptospo? ridium spp.. The overall infection rate of intestinal worms and protozoan were 4.72% and 24.31%，respectively. The prevalence rate of anemia was 34.68%. The prevalence rate of HIV was 8.10%. The co? infection rate of HIV and intestinal helminthes was 2.17%，and that of HIV and intestinal protozoan was 28.26%，of which the co?infection rate of Blastocystis hominis and HIV were 19.57% . There was a significant difference between the infection rates of Cryptosporidium spp. in the HIV ? positive group （13.04%）and HIV?negative group（4.70%） （P <0.05） . Conclusions The infection rate of intestinal protozoan is higher than that of intestinal helminthes in local residents. The HIV?positive population is more susceptible to the infection of Cryptosporidium spp.

Key words: HIV/AIDS；Intestinal parasite；Co?infection； Fuyang City

摘要：

目的 了解我国农村HIV/AIDS高流行地区HIV和肠道寄生虫合并感染状况。方法 采用横断面调查方法， 在安徽省阜阳市2个自然村开展流行病学调查， 检测居民HIV和寄生虫感染情况。结果 共调查769人， 其中720人参与了9 种常见肠道寄生虫的检测， 蛔虫、 钩虫、 鞭虫、 华支睾吸虫、 人芽囊原虫、 蓝氏贾第鞭毛虫、 阿米巴原虫、 隐孢子虫、 粪类圆线虫感染率分别为0.56%、 4.03%、 0.28%、 0.42%、 21.39%、 3.89%、 1.67%、 4.44%、 0。肠道蠕虫总感染率为4.72%， 原虫总感染率为24.31%； 贫血患病率为34.68%； HIV感染率为8.10%； HIV合并肠道蠕虫感染率为2.17%， 合并肠道原虫感染率为 28.26%， 其中合并人芽囊原虫感染率为19.57%； HIV阳性和HIV阴性人群合并隐孢子虫感染率分别为13.04%和4.70%， 两者差异有统计学意义 （P < 0.05）。结论 当地肠道蠕虫感染率低， 肠道原虫感染率高， HIV阳性人群对隐孢子虫易感性增高。

关键词: HIV/AIDS； 肠道寄生虫； 合并感染；阜阳市