Abstract:

Objective To study the cost ? effectiveness of different deworming schemes in demonstration plots of integrated control of parasitic diseases. Methods The cost?effectiveness was analyzed between mass drug administration and drug adminis? tration to focal population according to the different infection rates of parasites. Results In the demonstration plots of soil?born nematodes control, the costs for reducing one infected case and the cost for reducing 1% infection rate per ten thousand people in mass drug administration groups (Group 1 and Group 2) and drug administration to focal population were 20.73, 14.42 Yuan and 14.33 Yuan, and 1 700.49, 1 503.19 Yuan and 145.41 Yuan, respectively. In the demonstration plots of control of clonorchiasis si? nensis, the costs for reducing one infected case and the cost for reducing 1% infection rate per ten thousand people in mass drug ad? ministration group and drug administration to focal population were 31.03 Yuan and 37.01 Yuan, and 3 115.10 Yuan and 3841.38 Yuan, respectively. The multiple effectiveness indexes for control of soil ? transmitted nematodes in the mass drug administration groups (Group 1 and Group 2) and drug administration to focal population were 76.72, 80.27 and 97.64, respectively. The multiple effectiveness indexes for control of clonorchiasis sinensis in the mass drug administration group and the drug administration to focal population group were 112.93 and 65.49, respectively. Conclusions We should choose the deworming schemes not only to get a great reduction of human parasite infection rate and a rapid effective reduction of the source of infection, but also to make a full use of the limited funds on target population.

Key words: Parasitic disease, Integrated control, Demonstration plot, Cost-effectiveness, Multiple effectiveness index

摘要：

目的 分析寄生虫病示范区实施综合防治策略中不同驱虫方案的防治成本?效果。方法 方法 根据流行虫种和人群感染率的差异， 分别在土源性线虫病和华支睾吸虫病流行区实施全民服药驱虫和重点人群药物驱虫等不同的防治措施，并采用卫生经济学的方法对不同防治措施进行成本?效果分析。结果 结果 土源性线虫病示范区全民服药I组、 全民服药II组、重点人群服药组， 每减少1例感染者和每万人减少1％感染率的成本分别为20.73元和1 700.49元、 14.42元和1 503.19元、 14.33元和145.41元， 综合效果指数分别为76.72、 80.27、 97.64。华支睾吸虫病示范区全民服药组、 重点人群服药组， 每减少 1例感染者和每万人减少1％感染率成本分别为31.03元和3 115.10元、 37.01元和3 841.38元， 综合效果指数分别为112.93 和65.49。结论 结论 在选择防治方案时应根据当地的优势虫种、 人群差异等综合因素， 选择适合的药物驱虫方案或措施组合，以更好地科学利用卫生资源集中用于目标人群， 发挥其最佳的防治效果， 促进寄生虫病防治目标的实现。

关键词: 寄生虫病, 综合防治, 示范区, 成本?效果, 综合效果指数