Construction, expression and identification of a recombinant immunotoxin of scFv against Schistosoma japonicum

Chin J Schisto Control ›› 2010, Vol. 22 ›› Issue (2): 117-121.

Construction, expression and identification of a recombinant immunotoxin of scFv against Schistosoma japonicum

Li Hong¹, Zhu Xiao-juan², Gu Chun-yan¹, Ren Yong-ya¹, Xu Jing¹, Wang Zhong-can³, Li Yu-hua¹, Qiu Zhen-ning¹, Zhu Jin³, Feng Zhen-qing¹, Guan Xiao-hong¹

1 |Key Laboratory of Antibody Technique of Ministry of Health, Nanjing Medical University, Nanjing 210029, China|2 Department of Gastroenterology, Second Affiliated Hospital of Nanjing Medical University, China|3 Military Medicine Institute of Nanjing Military Region, China

Online:2010-04-15 Published:2010-04-16
Contact: Zhu Jin

抗日本血吸虫单链抗体免疫毒素的构建表达及生物学活性鉴定

李红¹|朱晓娟²|顾春艳¹|任勇亚¹|许静¹|王忠灿³|李玉华¹|仇镇宁¹|朱进³|冯振卿¹|管晓虹¹

1 南京医科大学卫生部抗体技术重点实验室（南京 210029）；2 南京医科大学第二附属医院消化医学中心；3 南京军区军事医学研究所

通讯作者: 朱进
基金资助:
国家高技术研究发展计划（863计划）（2006AA02Z415）

Abstract

Key words: Schistosoma japonicum, scFv, PE38KDEL, Recombinant immunotoxin

关键词: 日本血吸虫, scFv, PE38KDEL, 重组免疫毒素

CLC Number:

R383.24

LI Hong, SHU Xiao-Juan, GU Chun-Yan, REN Yong-Ya, XU Jing, WANG Zhong-Can, LI Yu-Hua, QIU Zhen-Ning, ZHU Jin, FENG Zhen-Qing, GUAN Xiao-Hong. Construction, expression and identification of a recombinant immunotoxin of scFv against Schistosoma japonicum[J]. Chin J Schisto Control, 2010, 22(2): 117-121.

李红, 朱晓娟, 顾春艳, 任勇亚, 许静, 王忠灿, 李玉华, 仇镇宁, 朱进, 冯振卿, 管晓虹. 抗日本血吸虫单链抗体免疫毒素的构建表达及生物学活性鉴定[J]. 中国血吸虫病防治杂志, 2010, 22(2): 117-121.

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